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Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes.

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Title: Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes.
Authors: Grumbach P; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Department of Psychiatry and Psychotherapy, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Bergische Landstraße 2, Duesseldorf, Germany., Kasper J; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany., Hipp JF; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland., Forsyth A; School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland; 85 Park Road, Grafton, Auckland, New Zealand., Valk SL; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany.; Max Planck School of Cognition; Stephanstraße 1A, Leipzig, Germany.; Max Planck Institute for Human Cognitive and Brain Sciences; Stephanstraße 1A, Leipzig, Germany., Muthukumaraswamy S; School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland; 85 Park Road, Grafton, Auckland, New Zealand., Eickhoff SB; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany., Schilbach L; Department of General Psychiatry 2, LVR-Klinikum Duesseldorf, Heinrich Heine University Duesseldorf; Bergische Landstraße 2, Duesseldorf, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilians University Munich; Nußbaumstraße 7, München, Germany., Dukart J; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany. j.dukart@fz-juelich.de.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany. j.dukart@fz-juelich.de.
Source: Nature communications [Nat Commun] 2025 Sep 09; Vol. 16 (1), pp. 8248. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes.
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  Data: <searchLink fieldCode="AU" term="%22Grumbach+P%22">Grumbach P</searchLink>; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Department of Psychiatry and Psychotherapy, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Bergische Landstraße 2, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Kasper+J%22">Kasper J</searchLink>; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Hipp+JF%22">Hipp JF</searchLink>; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forsyth+A%22">Forsyth A</searchLink>; School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland; 85 Park Road, Grafton, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Valk+SL%22">Valk SL</searchLink>; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany.; Max Planck School of Cognition; Stephanstraße 1A, Leipzig, Germany.; Max Planck Institute for Human Cognitive and Brain Sciences; Stephanstraße 1A, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Muthukumaraswamy+S%22">Muthukumaraswamy S</searchLink>; School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland; 85 Park Road, Grafton, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Eickhoff+SB%22">Eickhoff SB</searchLink>; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Schilbach+L%22">Schilbach L</searchLink>; Department of General Psychiatry 2, LVR-Klinikum Duesseldorf, Heinrich Heine University Duesseldorf; Bergische Landstraße 2, Duesseldorf, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilians University Munich; Nußbaumstraße 7, München, Germany.<br /><searchLink fieldCode="AU" term="%22Dukart+J%22">Dukart J</searchLink>; Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany. j.dukart@fz-juelich.de.; Institute of Systems Neuroscience, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University Duesseldorf; Moorenstraße 5, Duesseldorf, Germany. j.dukart@fz-juelich.de.
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