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Maximising olfactory deposition of a valproic acid (VPA)-loaded nanostructured lipid carriers (NLC) formulation.

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Title: Maximising olfactory deposition of a valproic acid (VPA)-loaded nanostructured lipid carriers (NLC) formulation.
Authors: Correia AC; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal., Farias G; Aptar Pharma, 27100 Le Vaudreuil, France., Nodilo LN; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia., Zadravec D; University Hospital Center 'Sestre milosrdnice', University of Zagreb, School of Dental Medicine, Zagreb, Croatia., Kalogjera L; University Hospital Center 'Sestre milosrdnice', Zagreb, Croatia., Moreira JN; CNC-UC - Center for Neurosciences and Cell Biology (CNC), Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal; Univ Coimbra - University of Coimbra, CIBB, Faculty of Pharmacy, Coimbra, Portugal., Sousa Lobo JM; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal., Hafner A; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia., Silva AC; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal; University Fernando Pessoa, FP-I3ID (Instituto de Investigação, Inovação e Desenvolvimento), FP-BHS (Biomedical and Health Sciences Research Unit), Faculty of Health Sciences, 4249 004 Porto, Portugal. Electronic address: anacatsil@gmail.com.
Source: International journal of pharmaceutics [Int J Pharm] 2025 Nov 10; Vol. 684, pp. 126166. Date of Electronic Publication: 2025 Sep 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Correia+AC%22">Correia AC</searchLink>; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Farias+G%22">Farias G</searchLink>; Aptar Pharma, 27100 Le Vaudreuil, France.<br /><searchLink fieldCode="AU" term="%22Nodilo+LN%22">Nodilo LN</searchLink>; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Zadravec+D%22">Zadravec D</searchLink>; University Hospital Center 'Sestre milosrdnice', University of Zagreb, School of Dental Medicine, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Kalogjera+L%22">Kalogjera L</searchLink>; University Hospital Center 'Sestre milosrdnice', Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Moreira+JN%22">Moreira JN</searchLink>; CNC-UC - Center for Neurosciences and Cell Biology (CNC), Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal; Univ Coimbra - University of Coimbra, CIBB, Faculty of Pharmacy, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Sousa+Lobo+JM%22">Sousa Lobo JM</searchLink>; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Hafner+A%22">Hafner A</searchLink>; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Silva+AC%22">Silva AC</searchLink>; University of Porto, UCIBIO, REQUIMTE, MEDTECH, Laboratory of Pharmaceutical Technology, Department, of Drug Sciences, Faculty of Pharmacy, Porto, Portugal; University of Porto, Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, Porto, Portugal; University Fernando Pessoa, FP-I3ID (Instituto de Investigação, Inovação e Desenvolvimento), FP-BHS (Biomedical and Health Sciences Research Unit), Faculty of Health Sciences, 4249 004 Porto, Portugal. Electronic address: anacatsil@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2025 Nov 10; Vol. 684, pp. 126166. <i>Date of Electronic Publication: </i>2025 Sep 13.
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              Text: 2025 Nov 10
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