View in EDS

Covariation MS uncovers a protein that controls cysteine catabolism.

Saved in:
Bibliographic Details
Title: Covariation MS uncovers a protein that controls cysteine catabolism.
Authors: Xiao H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. hpxiao@stanford.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. hpxiao@stanford.edu.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA. hpxiao@stanford.edu.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. hpxiao@stanford.edu., Ordonez M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Fink EC; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Covington TA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Woldemichael HB; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Chen J; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Jain MS; Department of Computer Science, Stanford University, Stanford, CA, USA.; Harvard Medical School, Boston, MA, USA., Rohatgi MH; Department of Computer Science, Stanford University, Stanford, CA, USA., Wei SM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Burger N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Sharif MA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Jan J; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Wang Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Petrocelli JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Blackmore K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Smythers AL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Zhang B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Gilbert M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Cheong H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Khetarpal SA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Smith A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Bogoslavski D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Lei Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Vaites LP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., McAllister FE; Calico Life Sciences, South San Francisco, CA, USA., Van Bruggen N; Calico Life Sciences, South San Francisco, CA, USA., Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Huttlin EL; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Mills EL; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Immunology, Harvard Medical School, Boston, MA, USA., Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Chouchani ET; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. edwardt_chouchani@dfci.harvard.edu.
Source: Nature [Nature] 2025 Nov; Vol. 647 (8088), pp. 268-276. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40963025
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Covariation MS uncovers a protein that controls cysteine catabolism.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. hpxiao@stanford.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. hpxiao@stanford.edu.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA. hpxiao@stanford.edu.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. hpxiao@stanford.edu.<br /><searchLink fieldCode="AU" term="%22Ordonez+M%22">Ordonez M</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fink+EC%22">Fink EC</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Covington+TA%22">Covington TA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Woldemichael+HB%22">Woldemichael HB</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jain+MS%22">Jain MS</searchLink>; Department of Computer Science, Stanford University, Stanford, CA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rohatgi+MH%22">Rohatgi MH</searchLink>; Department of Computer Science, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wei+SM%22">Wei SM</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Burger+N%22">Burger N</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sharif+MA%22">Sharif MA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jan+J%22">Jan J</searchLink>; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Petrocelli+JJ%22">Petrocelli JJ</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Blackmore+K%22">Blackmore K</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Smythers+AL%22">Smythers AL</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gilbert+M%22">Gilbert M</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cheong+H%22">Cheong H</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Khetarpal+SA%22">Khetarpal SA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+A%22">Smith A</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bogoslavski+D%22">Bogoslavski D</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vaites+LP%22">Vaites LP</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McAllister+FE%22">McAllister FE</searchLink>; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Bruggen+N%22">Van Bruggen N</searchLink>; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+KA%22">Donovan KA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Huttlin+EL%22">Huttlin EL</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mills+EL%22">Mills EL</searchLink>; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Immunology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fischer+ES%22">Fischer ES</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chouchani+ET%22">Chouchani ET</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. edwardt_chouchani@dfci.harvard.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Nov; Vol. 647 (8088), pp. 268-276. <i>Date of Electronic Publication: </i>2025 Sep 17.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40963025
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41586-025-09535-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 268
    Titles:
      – TitleFull: Covariation MS uncovers a protein that controls cysteine catabolism.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Xiao H
      – PersonEntity:
          Name:
            NameFull: Ordonez M
      – PersonEntity:
          Name:
            NameFull: Fink EC
      – PersonEntity:
          Name:
            NameFull: Covington TA
      – PersonEntity:
          Name:
            NameFull: Woldemichael HB
      – PersonEntity:
          Name:
            NameFull: Chen J
      – PersonEntity:
          Name:
            NameFull: Jain MS
      – PersonEntity:
          Name:
            NameFull: Rohatgi MH
      – PersonEntity:
          Name:
            NameFull: Wei SM
      – PersonEntity:
          Name:
            NameFull: Burger N
      – PersonEntity:
          Name:
            NameFull: Sharif MA
      – PersonEntity:
          Name:
            NameFull: Jan J
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Petrocelli JJ
      – PersonEntity:
          Name:
            NameFull: Blackmore K
      – PersonEntity:
          Name:
            NameFull: Smythers AL
      – PersonEntity:
          Name:
            NameFull: Zhang B
      – PersonEntity:
          Name:
            NameFull: Gilbert M
      – PersonEntity:
          Name:
            NameFull: Cheong H
      – PersonEntity:
          Name:
            NameFull: Khetarpal SA
      – PersonEntity:
          Name:
            NameFull: Smith A
      – PersonEntity:
          Name:
            NameFull: Bogoslavski D
      – PersonEntity:
          Name:
            NameFull: Lei Y
      – PersonEntity:
          Name:
            NameFull: Vaites LP
      – PersonEntity:
          Name:
            NameFull: McAllister FE
      – PersonEntity:
          Name:
            NameFull: Van Bruggen N
      – PersonEntity:
          Name:
            NameFull: Donovan KA
      – PersonEntity:
          Name:
            NameFull: Huttlin EL
      – PersonEntity:
          Name:
            NameFull: Mills EL
      – PersonEntity:
          Name:
            NameFull: Fischer ES
      – PersonEntity:
          Name:
            NameFull: Chouchani ET
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: 2025 Nov
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
          Numbering:
            – Type: volume
              Value: 647
            – Type: issue
              Value: 8088
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1