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ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.

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Title: ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.
Authors: Cho SH; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea., Choi B; Department of Computer Science, Hanyang University, Seoul, Republic of Korea., Lee J; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Lee YS; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Baek MO; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea., Lee YJ; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea., Gil CO; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea., Choi MK; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea., Khaliq SA; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea., Maham S; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea., Hyun JK; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea., Roh G; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Choi H; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Lee S; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Bae SH; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Lee S; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Park HJ; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Ahn JH; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Lee NY; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea., Kang BC; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Seo YK; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Lim BK; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea., Nam JH; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Rho M; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.; Department of Biomedical Informatics, Hanyang University, Seoul, Republic of Korea., Yoon MS; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
Source: Theranostics [Theranostics] 2025 Aug 16; Vol. 15 (17), pp. 8964-8984. Date of Electronic Publication: 2025 Aug 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
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  Data: ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.
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  Data: <searchLink fieldCode="AU" term="%22Cho+SH%22">Cho SH</searchLink>; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+B%22">Choi B</searchLink>; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YS%22">Lee YS</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Baek+MO%22">Baek MO</searchLink>; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YJ%22">Lee YJ</searchLink>; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Gil+CO%22">Gil CO</searchLink>; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+MK%22">Choi MK</searchLink>; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Khaliq+SA%22">Khaliq SA</searchLink>; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Maham+S%22">Maham S</searchLink>; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hyun+JK%22">Hyun JK</searchLink>; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Roh+G%22">Roh G</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+SH%22">Bae SH</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HJ%22">Park HJ</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+NY%22">Lee NY</searchLink>; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+BC%22">Kang BC</searchLink>; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Seo+YK%22">Seo YK</searchLink>; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+BK%22">Lim BK</searchLink>; Department of Biomedical Science, Jungwon University, Goesan-gun, Chungcheongbuk-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+JH%22">Nam JH</searchLink>; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.; Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Rho+M%22">Rho M</searchLink>; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.; Department of Biomedical Informatics, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+MS%22">Yoon MS</searchLink>; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.; Department of Molecular Medicine, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2025 Aug 16; Vol. 15 (17), pp. 8964-8984. <i>Date of Electronic Publication: </i>2025 Aug 16 (<i>Print Publication: </i>2025).
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