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Targeting IL-4/IL-13 Signaling Pathways in Chronic Rhinosinusitis with Nasal Polyps: From Mechanisms to Therapies.

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Title: Targeting IL-4/IL-13 Signaling Pathways in Chronic Rhinosinusitis with Nasal Polyps: From Mechanisms to Therapies.
Authors: Chen J; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Zhang C; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Zhang Q; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Cheng F; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Wang Y; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Xue S; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Yang Y; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Guo W; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Liu J; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Xue K; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Zhang Y; Center for Immunological and Metabolic Diseases, the First Affiliated Hospital of Xi'an JiaoTong University, JiaoTong University, Xi'an, Shaanxi, China.; Key Laboratory for ImmunoHealth of Shaanxi Province, Xi'an JiaoTong University, Xi'an, Shaanxi, China., Wang D; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Hu L; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Wang H; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China., Sun X; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China. laryngeal@163.com.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China. laryngeal@163.com.; Department of Otolaryngology, People's Hospital of Shigatse City, Shigatse, China. laryngeal@163.com.
Source: Clinical reviews in allergy & immunology [Clin Rev Allergy Immunol] 2025 Sep 18; Vol. 68 (1), pp. 87. Date of Electronic Publication: 2025 Sep 18.
Publication Type: Journal Article; Review
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9504368 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0267 (Electronic) Linking ISSN: 10800549 NLM ISO Abbreviation: Clin Rev Allergy Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting IL-4/IL-13 Signaling Pathways in Chronic Rhinosinusitis with Nasal Polyps: From Mechanisms to Therapies.
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  Data: <searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Cheng+F%22">Cheng F</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Xue+S%22">Xue S</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Guo+W%22">Guo W</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Xue+K%22">Xue K</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Center for Immunological and Metabolic Diseases, the First Affiliated Hospital of Xi'an JiaoTong University, JiaoTong University, Xi'an, Shaanxi, China.; Key Laboratory for ImmunoHealth of Shaanxi Province, Xi'an JiaoTong University, Xi'an, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Hu+L%22">Hu L</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China.<br /><searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; High Altitude Rhinology Research Center, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China. laryngeal@163.com.; ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai, 200031, China. laryngeal@163.com.; Department of Otolaryngology, People's Hospital of Shigatse City, Shigatse, China. laryngeal@163.com.
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  Data: <searchLink fieldCode="JN" term="%229504368%22">Clinical reviews in allergy & immunology</searchLink> [Clin Rev Allergy Immunol] 2025 Sep 18; Vol. 68 (1), pp. 87. <i>Date of Electronic Publication: </i>2025 Sep 18.
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