PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids.

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Title: PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids.
Authors: Ljubikj T; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., Mars MZ; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., van der Geest AT; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., Jakobs CE; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., Bessler N; Princess Máxima Center for Pedriatic Onocology, Utrecht University, Utrecht 3584 CS, The Netherlands., Donega V; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.; Department of Anatomy and Neurosciences, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands.; Amsterdam Neuroscience, Cellular and Molecular Mechanisms, Amsterdam 1081 HV, The Netherlands., van den Oetelaar XPRM; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., de Wit M; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.
Source: Brain : a journal of neurology [Brain] 2026 Mar 05; Vol. 149 (3), pp. 801-817.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids.
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  Data: <searchLink fieldCode="AU" term="%22Ljubikj+T%22">Ljubikj T</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mars+MZ%22">Mars MZ</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Geest+AT%22">van der Geest AT</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jakobs+CE%22">Jakobs CE</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bessler+N%22">Bessler N</searchLink>; Princess Máxima Center for Pedriatic Onocology, Utrecht University, Utrecht 3584 CS, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Donega+V%22">Donega V</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.; Department of Anatomy and Neurosciences, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands.; Amsterdam Neuroscience, Cellular and Molecular Mechanisms, Amsterdam 1081 HV, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Oetelaar+XPRM%22">van den Oetelaar XPRM</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Wit+M%22">de Wit M</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pasterkamp+RJ%22">Pasterkamp RJ</searchLink>; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht 3584 CG, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220372537%22">Brain : a journal of neurology</searchLink> [Brain] 2026 Mar 05; Vol. 149 (3), pp. 801-817.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372537 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200068950%22">00068950 </searchLink><i>NLM ISO Abbreviation: </i>Brain <i>Subsets: </i>MEDLINE
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        Value: 10.1093/brain/awaf340
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              Text: 2026 Mar 05
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