Safety and efficacy of KRAS antisense oligonucleotides and RIG-I agonists delivered by extracellular vesicles for pancreatic cancer peritoneal metastasis treatment.

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Bibliographic Details
Title: Safety and efficacy of KRAS antisense oligonucleotides and RIG-I agonists delivered by extracellular vesicles for pancreatic cancer peritoneal metastasis treatment.
Authors: Nguyen TTT; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Dang XTT; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Phung CD; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tran LTN; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Do NTP; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Yeo EYM; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tran NM; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Yeo BZJ; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lixuan CP; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Institute of Structural Biology, Nanyang Technological University, Singapore., Nguyen NTH; Vinmec-VinUni Institute of Immunology, Vin University, Viet Nam., Nguyen HX; Vinmec-VinUni Institute of Immunology, Vin University, Viet Nam; Vinmec Hitech Center, Vinmec Healthcare System, Viet Nam., Ngo HT; Center for Research and Production of Vaccines and Biologicals, Viet Nam., Bonney GK; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Institute for Health Innovation and Technology, National University of Singapore, Singapore., Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Institute of Structural Biology, Nanyang Technological University, Singapore., Le MTN; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cancer Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Institute of Molecular and Cell Biology, A*STAR, Singapore. Electronic address: phcltnm@nus.edu.sg.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Nov 10; Vol. 387, pp. 114239. Date of Electronic Publication: 2025 Sep 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
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