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Metronidazole exposure-response and safety in infants.

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Title: Metronidazole exposure-response and safety in infants.
Authors: Randell RL; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Balevic SJ; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Greenberg RG; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Cohen-Wolkowiez M; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Smith MJ; Department of Pediatrics, Duke University, Durham, North Carolina, USA., Benjamin DK Jr; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Bendel C; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Bliss JM; Department of Pediatrics, Division of Neonatology, University of Rochester Medical Center, Rochester, New York, USA., Chaaban H; Department of Pediatrics, Division of Neonatology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA., Chhabra R; Department of Pediatrics, Division of Neonatology, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, New Jersey, USA., Dammann CEL; Department of Pediatrics, Tufts Medical Center, Tufts University, Boston, Massachusetts, USA., Downey LC; Department of Pediatrics, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA., Hornik CD; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Hussain N; Department of Pediatrics, Division of Neonatology, Connecticut Children's, Hartford, Connecticut, USA., Laughon MM; Department of Pediatrics, Division of Neonatal-Perinatal Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lavery A; Children's Hospital of Orange County, Orange, California, USA., Moya F; Pediatrix Medical Group, Austin, Texas, USA., Saxonhouse M; Department of Pediatrics, Division of Neonatology, Levine Children's Hospital, Wake Forest School of Medicine Charlotte Campus, Atrium Healthcare, Charlotte, North Carolina, USA., Sokol GM; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Trembath A; Division of Neonatal-Perinatal Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Weitkamp J-H; Mildred Stahlman Division of Neonatology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Hornik CP; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.
Corporate Authors: Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Nov 05; Vol. 69 (11), pp. e0037725. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Randell+RL%22">Randell RL</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Balevic+SJ%22">Balevic SJ</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+RG%22">Greenberg RG</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Cohen-Wolkowiez+M%22">Cohen-Wolkowiez M</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Smith+MJ%22">Smith MJ</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Benjamin+DK+Jr%22">Benjamin DK Jr</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Bendel+C%22">Bendel C</searchLink>; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Bliss+JM%22">Bliss JM</searchLink>; Department of Pediatrics, Division of Neonatology, University of Rochester Medical Center, Rochester, New York, USA.<br /><searchLink fieldCode="AU" term="%22Chaaban+H%22">Chaaban H</searchLink>; Department of Pediatrics, Division of Neonatology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Chhabra+R%22">Chhabra R</searchLink>; Department of Pediatrics, Division of Neonatology, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Dammann+CEL%22">Dammann CEL</searchLink>; Department of Pediatrics, Tufts Medical Center, Tufts University, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Downey+LC%22">Downey LC</searchLink>; Department of Pediatrics, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Hornik+CD%22">Hornik CD</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Hussain+N%22">Hussain N</searchLink>; Department of Pediatrics, Division of Neonatology, Connecticut Children's, Hartford, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Laughon+MM%22">Laughon MM</searchLink>; Department of Pediatrics, Division of Neonatal-Perinatal Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Lavery+A%22">Lavery A</searchLink>; Children's Hospital of Orange County, Orange, California, USA.<br /><searchLink fieldCode="AU" term="%22Moya+F%22">Moya F</searchLink>; Pediatrix Medical Group, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Saxonhouse+M%22">Saxonhouse M</searchLink>; Department of Pediatrics, Division of Neonatology, Levine Children's Hospital, Wake Forest School of Medicine Charlotte Campus, Atrium Healthcare, Charlotte, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Sokol+GM%22">Sokol GM</searchLink>; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Trembath+A%22">Trembath A</searchLink>; Division of Neonatal-Perinatal Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Weitkamp+J-H%22">Weitkamp J-H</searchLink>; Mildred Stahlman Division of Neonatology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Hornik+CP%22">Hornik CP</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2025 Nov 05; Vol. 69 (11), pp. e0037725. <i>Date of Electronic Publication: </i>2025 Sep 19.
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