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Differentiation latency and dormancy signatures define fetal liver hematopoietic stem cells at single-cell resolution.

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Title: Differentiation latency and dormancy signatures define fetal liver hematopoietic stem cells at single-cell resolution.
Authors: Ishida T; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Mercoli J; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Heck AM; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Phelps I; Department of Pediatrics, University of Washington, Seattle, WA, USA., Varnum-Finney B; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Dozono S; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Nourigat-McKay C; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Kraskouskas K; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Wellington R; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Waltner O; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jackson DL; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Delaney C; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA., Rafii S; Division of Regenerative Medicine, Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Bernstein ID; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA., Aldinger KA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, WA, USA., Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Zhao HG; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: hzhao2@fredhutch.org., Hadland B; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: bhadland@fredhutch.org.
Corporate Authors: Birth Defects Research Laboratory (BDRL); Department of Pediatrics, University of Washington, Seattle, WA, USA.
Source: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116289. Date of Electronic Publication: 2025 Sep 18.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Differentiation latency and dormancy signatures define fetal liver hematopoietic stem cells at single-cell resolution.
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  Data: <searchLink fieldCode="AU" term="%22Ishida+T%22">Ishida T</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Mercoli+J%22">Mercoli J</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Heck+AM%22">Heck AM</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Phelps+I%22">Phelps I</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Varnum-Finney+B%22">Varnum-Finney B</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dozono+S%22">Dozono S</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Nourigat-McKay+C%22">Nourigat-McKay C</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kraskouskas+K%22">Kraskouskas K</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wellington+R%22">Wellington R</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Waltner+O%22">Waltner O</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+DL%22">Jackson DL</searchLink>; Department of Genome Sciences, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Delaney+C%22">Delaney C</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rafii+S%22">Rafii S</searchLink>; Division of Regenerative Medicine, Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+ID%22">Bernstein ID</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Aldinger+KA%22">Aldinger KA</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA; Department of Neurology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Trapnell+C%22">Trapnell C</searchLink>; Department of Genome Sciences, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+HG%22">Zhao HG</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: hzhao2@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Hadland+B%22">Hadland B</searchLink>; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: bhadland@fredhutch.org.
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  Data: <searchLink fieldCode="CA" term="%22Birth+Defects+Research+Laboratory+%28BDRL%29%22">Birth Defects Research Laboratory (BDRL)</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116289. <i>Date of Electronic Publication: </i>2025 Sep 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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