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Dual character of surface engineering on SN38 prodrug nano-assemblies: divergent effects on in vitro and in vivo behavior.

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Title: Dual character of surface engineering on SN38 prodrug nano-assemblies: divergent effects on in vitro and in vivo behavior.
Authors: Li YQ; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.; Department of Bioengineering, Graduate School of Engineering, the University of Tokyo, Tokyo, 113-0033, Japan., Kuang ZY; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Zhang BY; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Hao YZ; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Li LX; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Zhang JX; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Xiao YF; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Zhang BW; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China., Shi XB; Department of Pharmacy, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, 121001, Liaoning, China., Pu XH; State Key Laboratory of Antiviral Drugs, School of Pharmacy, Henan University, Kaifeng, 475004, Henan, China., He ZG; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. hezhonggui@syphu.edu.cn.; State Key Laboratory of Antiviral Drugs, School of Pharmacy, Henan University, Kaifeng, 475004, Henan, China. hezhonggui@syphu.edu.cn.; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang, 110016, China. hezhonggui@syphu.edu.cn., Sun BJ; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. sunbingjun@syphu.edu.cn.; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang, 110016, China. sunbingjun@syphu.edu.cn.
Source: Military Medical Research [Mil Med Res] 2025 Sep 22; Vol. 12 (1), pp. 60. Date of Electronic Publication: 2025 Sep 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101643181 Publication Model: Electronic Cited Medium: Internet ISSN: 2054-9369 (Electronic) Linking ISSN: 20549369 NLM ISO Abbreviation: Mil Med Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual character of surface engineering on SN38 prodrug nano-assemblies: divergent effects on in vitro and in vivo behavior.
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  Data: <searchLink fieldCode="AU" term="%22Li+YQ%22">Li YQ</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.; Department of Bioengineering, Graduate School of Engineering, the University of Tokyo, Tokyo, 113-0033, Japan.<br /><searchLink fieldCode="AU" term="%22Kuang+ZY%22">Kuang ZY</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Zhang+BY%22">Zhang BY</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Hao+YZ%22">Hao YZ</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Li+LX%22">Li LX</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Zhang+JX%22">Zhang JX</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Xiao+YF%22">Xiao YF</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Zhang+BW%22">Zhang BW</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.<br /><searchLink fieldCode="AU" term="%22Shi+XB%22">Shi XB</searchLink>; Department of Pharmacy, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, 121001, Liaoning, China.<br /><searchLink fieldCode="AU" term="%22Pu+XH%22">Pu XH</searchLink>; State Key Laboratory of Antiviral Drugs, School of Pharmacy, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22He+ZG%22">He ZG</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. hezhonggui@syphu.edu.cn.; State Key Laboratory of Antiviral Drugs, School of Pharmacy, Henan University, Kaifeng, 475004, Henan, China. hezhonggui@syphu.edu.cn.; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang, 110016, China. hezhonggui@syphu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Sun+BJ%22">Sun BJ</searchLink>; Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. sunbingjun@syphu.edu.cn.; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang, 110016, China. sunbingjun@syphu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101643181%22">Military Medical Research</searchLink> [Mil Med Res] 2025 Sep 22; Vol. 12 (1), pp. 60. <i>Date of Electronic Publication: </i>2025 Sep 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101643181 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2054-9369 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220549369%22">20549369 </searchLink><i>NLM ISO Abbreviation: </i>Mil Med Res <i>Subsets: </i>MEDLINE
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