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Drugs targeting the NO-sGC-cGMP pathway in the treatment of patients with COPD-associated pulmonary hypertension: a systematic review.

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Title: Drugs targeting the NO-sGC-cGMP pathway in the treatment of patients with COPD-associated pulmonary hypertension: a systematic review.
Authors: Alqarni AA; Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.; Respiratory Therapy Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., Alghamdi SA; Respiratory Care Department, AlSalama Hospital, Jeddah, Saudi Arabia., Aldhahir AM; Respiratory Therapy Program, Department of Nursing, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia., Alqahtani JS; Department of Respiratory Care, Prince Sultan Military College of Health Sciences, Dammam, Saudi Arabia., Siraj RA; Department of Respiratory Care, College of Applied Medical Sciences, King Faisal University, Al Ahsa, Saudi Arabia., Alasimi AH; Department of Respiratory Therapy, Georgia State University, Atlanta, GA, United States., Bintalib HM; Department of Respiratory Care, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.; King Abdullah International Medical Research Centre, Jeddah, Saudi Arabia., AlGarni AA; King Abdulaziz Hospital, The Ministry of National Guard Health Affairs, Al Ahsa, Saudi Arabia.; King Saud bin Abdulaziz University for Health Sciences, College of Applied Medical Sciences, Al Ahsa, Saudi Arabia., Majrshi M; Respiratory Therapy Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom., Alshabasy AM; Anesthesia and Critical Care Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia., AlBahrani S; Infectious Disease Unit, Specialty Internal Medicine, King Fahd Military Medical Complex, Dhahran, Saudi Arabia.; College of Medicine, Imam Abdulrahaman Bin Faisal University, Dammam, Saudi Arabia., Alwafi H; Department of Clinical Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Sep 05; Vol. 16, pp. 1641932. Date of Electronic Publication: 2025 Sep 05 (Print Publication: 2025).
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Alqarni+AA%22">Alqarni AA</searchLink>; Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.; Respiratory Therapy Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alghamdi+SA%22">Alghamdi SA</searchLink>; Respiratory Care Department, AlSalama Hospital, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aldhahir+AM%22">Aldhahir AM</searchLink>; Respiratory Therapy Program, Department of Nursing, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alqahtani+JS%22">Alqahtani JS</searchLink>; Department of Respiratory Care, Prince Sultan Military College of Health Sciences, Dammam, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Siraj+RA%22">Siraj RA</searchLink>; Department of Respiratory Care, College of Applied Medical Sciences, King Faisal University, Al Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alasimi+AH%22">Alasimi AH</searchLink>; Department of Respiratory Therapy, Georgia State University, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Bintalib+HM%22">Bintalib HM</searchLink>; Department of Respiratory Care, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.; King Abdullah International Medical Research Centre, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22AlGarni+AA%22">AlGarni AA</searchLink>; King Abdulaziz Hospital, The Ministry of National Guard Health Affairs, Al Ahsa, Saudi Arabia.; King Saud bin Abdulaziz University for Health Sciences, College of Applied Medical Sciences, Al Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Majrshi+M%22">Majrshi M</searchLink>; Respiratory Therapy Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Alshabasy+AM%22">Alshabasy AM</searchLink>; Anesthesia and Critical Care Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22AlBahrani+S%22">AlBahrani S</searchLink>; Infectious Disease Unit, Specialty Internal Medicine, King Fahd Military Medical Complex, Dhahran, Saudi Arabia.; College of Medicine, Imam Abdulrahaman Bin Faisal University, Dammam, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alwafi+H%22">Alwafi H</searchLink>; Department of Clinical Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
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