Effectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial.

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Title: Effectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial.
Authors: Chu CS; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Non-invasive Neuromodulation Consortium for Mental Disorders, Society of Psychophysiology, Taipei, Taiwan., Chang HA; Non-invasive Neuromodulation Consortium for Mental Disorders, Society of Psychophysiology, Taipei, Taiwan.; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Lin YT; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Shen HC; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Department of Business Management, National Sun Yat-Sen University, Kaohsiung, Taiwan., Liang CK; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan., Hsu YH; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan., Pan CC; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Kuo HY; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Liang WZ; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Department of Pharmacy and Master Program, College of Pharmacy and Health Care, Tajen University, Pingtung, Taiwan., Chen SL; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Drug Development and Value Creation Research Center and MSc Program in Tropical, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan., Chen CS; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Psychiatry, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Nov; Vol. 108 (1), pp. 298-311. Date of Electronic Publication: 2025 Sep 22.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Chu+CS%22">Chu CS</searchLink>; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Non-invasive Neuromodulation Consortium for Mental Disorders, Society of Psychophysiology, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+HA%22">Chang HA</searchLink>; Non-invasive Neuromodulation Consortium for Mental Disorders, Society of Psychophysiology, Taipei, Taiwan.; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YT%22">Lin YT</searchLink>; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+HC%22">Shen HC</searchLink>; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Department of Business Management, National Sun Yat-Sen University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+CK%22">Liang CK</searchLink>; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+YH%22">Hsu YH</searchLink>; Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Division of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pan+CC%22">Pan CC</searchLink>; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+HY%22">Kuo HY</searchLink>; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+WZ%22">Liang WZ</searchLink>; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; Department of Pharmacy and Master Program, College of Pharmacy and Health Care, Tajen University, Pingtung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+SL%22">Chen SL</searchLink>; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Drug Development and Value Creation Research Center and MSc Program in Tropical, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CS%22">Chen CS</searchLink>; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Psychiatry, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2025 Nov; Vol. 108 (1), pp. 298-311. <i>Date of Electronic Publication: </i>2025 Sep 22.
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  Data: Journal Article; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1177/13872877251376547
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        Text: English
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        StartPage: 298
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      – TitleFull: Effectiveness and safety of high-definition transcranial direct current stimulation in patients with mild cognitive impairment: A randomized, triple-blind, sham-controlled trial.
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            – D: 01
              M: 11
              Text: 2025 Nov
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              Y: 2025
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