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Atenolol rescues premature mortality in genetic mouse models of sudden unexpected death in epilepsy.

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Title: Atenolol rescues premature mortality in genetic mouse models of sudden unexpected death in epilepsy.
Authors: Soh MS; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Hu A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Kuanyshbek A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Mohamed Syazwan ES; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Lee HM; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., McKenzie CE; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Phillips AM; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; School of Biosciences, University of Melbourne, Melbourne, Victoria, Australia., Bleakley LE; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Semsarian C; Agnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Scheffer IE; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.; Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria, Australia., Berkovic SF; Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia., Reid CA; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.
Source: Epilepsia [Epilepsia] 2026 Jan; Vol. 67 (1), pp. 448-462. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Atenolol rescues premature mortality in genetic mouse models of sudden unexpected death in epilepsy.
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  Data: <searchLink fieldCode="AU" term="%22Soh+MS%22">Soh MS</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hu+A%22">Hu A</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kuanyshbek+A%22">Kuanyshbek A</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Mohamed+Syazwan+ES%22">Mohamed Syazwan ES</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+HM%22">Lee HM</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McKenzie+CE%22">McKenzie CE</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Phillips+AM%22">Phillips AM</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; School of Biosciences, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Bleakley+LE%22">Bleakley LE</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Semsarian+C%22">Semsarian C</searchLink>; Agnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Scheffer+IE%22">Scheffer IE</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.; Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Berkovic+SF%22">Berkovic SF</searchLink>; Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Reid+CA%22">Reid CA</searchLink>; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.
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  Data: <searchLink fieldCode="JN" term="%222983306R%22">Epilepsia</searchLink> [Epilepsia] 2026 Jan; Vol. 67 (1), pp. 448-462. <i>Date of Electronic Publication: </i>2025 Sep 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Blackwell+Science%22">Blackwell Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2983306R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-1167 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200139580%22">00139580 </searchLink><i>NLM ISO Abbreviation: </i>Epilepsia <i>Subsets: </i>MEDLINE
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        Value: 10.1111/epi.18642
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              Text: 2026 Jan
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