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Increased expression of ATase1/NAT8B or ATase2/NAT8 in the mouse results in an autistic-like phenotype with altered dendritic branching and spine formation.

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Title: Increased expression of ATase1/NAT8B or ATase2/NAT8 in the mouse results in an autistic-like phenotype with altered dendritic branching and spine formation.
Authors: Kalimuthu B; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; National University of Singapore, Singapore, Singapore., Lu H; School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA., Steenhagen A; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Dong Q; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medical Genetics and Neurology, University of Wisconsin-Madison, Madison, WI, USA., Gray M; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Rigby MJ; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Endresen A; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Boehringer-Ingelheim, Ridgefield, CT, USA., Chang Q; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medical Genetics and Neurology, University of Wisconsin-Madison, Madison, WI, USA., Li L; School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Puglielli L; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Geriatric Research Education Clinical Center, Veterans Affairs Medical Center, Madison, WI, USA. lp1@medicine.wisc.edu.; Department of Neuroscience, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jan; Vol. 31 (1), pp. 1-15. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased expression of ATase1/NAT8B or ATase2/NAT8 in the mouse results in an autistic-like phenotype with altered dendritic branching and spine formation.
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  Data: <searchLink fieldCode="AU" term="%22Kalimuthu+B%22">Kalimuthu B</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lu+H%22">Lu H</searchLink>; School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Steenhagen+A%22">Steenhagen A</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Dong+Q%22">Dong Q</searchLink>; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medical Genetics and Neurology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Gray+M%22">Gray M</searchLink>; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Rigby+MJ%22">Rigby MJ</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Endresen+A%22">Endresen A</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Boehringer-Ingelheim, Ridgefield, CT, USA.<br /><searchLink fieldCode="AU" term="%22Chang+Q%22">Chang Q</searchLink>; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medical Genetics and Neurology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Puglielli+L%22">Puglielli L</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Geriatric Research Education Clinical Center, Veterans Affairs Medical Center, Madison, WI, USA. lp1@medicine.wisc.edu.; Department of Neuroscience, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Jan; Vol. 31 (1), pp. 1-15. <i>Date of Electronic Publication: </i>2025 Sep 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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