Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition.

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Title: Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition.
Authors: Onder G; Department of Biochemistry and Molecular Biology, Health Sciences Institute, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Ozdemir O; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Biology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Taylan F; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden., Canpolat C; Department of Pediatric Oncology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Yalcin K; Department of Pediatric Hematology, Bahçeşehir University, Goztepe Medical Park Hospital, Istanbul, Türkiye.; Department of Medical Biotechnology, Health Sciences Institute, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Erbey F; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye., Sozmen BO; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye., Asarcikli F; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye., Bayhan T; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.; Department of Pediatric Hematology and Oncology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye., Akcabelen YM; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye., Yarali N; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.; Department of Pediatric Hematology and Oncology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye., Ozbek NY; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye., Bozkaya IO; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye., Kacar D; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye., Ergun B; GENIVA Information Health Services Company, Istanbul, Türkiye., Akkus A; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Translational Medicine, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Albayrak D; Department of Pediatric Hematology, Samsun Medical Park Hospital, Samsun, Türkiye., Ince E; Department of Pediatric Hematology and Oncology, Faculty of Medicine, Ankara University, Ankara, Türkiye., Demirsoy U; Department of Pediatric Oncology, Faculty of Medicine, Kocaeli University, Izmit, Kocaeli, Türkiye., Ozdemir GN; Department of Pediatric Hematology, Faculty of Medicine, Istinye University, Istanbul, Türkiye., Dogru O; Department of Pediatric Hematology, Biruni University, Istanbul, Türkiye., Aras S; Department of Pediatric Hematology Oncology, Hatay Training and Research Hospital, Hatay, Türkiye., Aydin E; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Translational Medicine, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Unal B; Department of Cancer Genetics, Umraniye Traning and Research Hospital, Istanbul, Türkiye., Amanvermez U; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Genome Studies, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Dogan OA; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Genetics, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Akyoney S; Department of Bioinformatics and Biostatistic, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye., Sayitoglu M; Department of Genetics, Istanbul University, Institute of Aziz Sancar Experimental Medicine, Istanbul, Türkiye., Nordgren A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Bugra Agaoglu N; Department of Cancer Genetics, Umraniye Traning and Research Hospital, Istanbul, Türkiye.; Department of Neurology, Krankenhaus Nordwest, Frankfurt, Germany., Ozbek U; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; International Biomedicine and Genome Institute (iBG), Izmir Dokuz Eylül University, Izmir, Türkiye., Ng OH; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Biology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.
Source: Frontiers in genetics [Front Genet] 2025 Sep 09; Vol. 16, pp. 1624306. Date of Electronic Publication: 2025 Sep 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101560621 Publication Model: eCollection Cited Medium: Print ISSN: 1664-8021 (Print) Linking ISSN: 16648021 NLM ISO Abbreviation: Front Genet Subsets: PubMed not MEDLINE
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  Data: Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition.
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  Data: <searchLink fieldCode="AU" term="%22Onder+G%22">Onder G</searchLink>; Department of Biochemistry and Molecular Biology, Health Sciences Institute, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ozdemir+O%22">Ozdemir O</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Biology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Taylan+F%22">Taylan F</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Canpolat+C%22">Canpolat C</searchLink>; Department of Pediatric Oncology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Yalcin+K%22">Yalcin K</searchLink>; Department of Pediatric Hematology, Bahçeşehir University, Goztepe Medical Park Hospital, Istanbul, Türkiye.; Department of Medical Biotechnology, Health Sciences Institute, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Erbey+F%22">Erbey F</searchLink>; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Sozmen+BO%22">Sozmen BO</searchLink>; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Asarcikli+F%22">Asarcikli F</searchLink>; Department of Pediatric Hematology and Oncology, Hospital of Koç University, Istanbul, Türkiye.; Department of Pediatric, School of Medicine, Koç University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Bayhan+T%22">Bayhan T</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.; Department of Pediatric Hematology and Oncology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Akcabelen+YM%22">Akcabelen YM</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Yarali+N%22">Yarali N</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.; Department of Pediatric Hematology and Oncology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ozbek+NY%22">Ozbek NY</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Bozkaya+IO%22">Bozkaya IO</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Kacar+D%22">Kacar D</searchLink>; Department of Pediatric Hematology and Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ergun+B%22">Ergun B</searchLink>; GENIVA Information Health Services Company, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Akkus+A%22">Akkus A</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Translational Medicine, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Albayrak+D%22">Albayrak D</searchLink>; Department of Pediatric Hematology, Samsun Medical Park Hospital, Samsun, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ince+E%22">Ince E</searchLink>; Department of Pediatric Hematology and Oncology, Faculty of Medicine, Ankara University, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Demirsoy+U%22">Demirsoy U</searchLink>; Department of Pediatric Oncology, Faculty of Medicine, Kocaeli University, Izmit, Kocaeli, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ozdemir+GN%22">Ozdemir GN</searchLink>; Department of Pediatric Hematology, Faculty of Medicine, Istinye University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Dogru+O%22">Dogru O</searchLink>; Department of Pediatric Hematology, Biruni University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Aras+S%22">Aras S</searchLink>; Department of Pediatric Hematology Oncology, Hatay Training and Research Hospital, Hatay, Türkiye.<br /><searchLink fieldCode="AU" term="%22Aydin+E%22">Aydin E</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Translational Medicine, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Unal+B%22">Unal B</searchLink>; Department of Cancer Genetics, Umraniye Traning and Research Hospital, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Amanvermez+U%22">Amanvermez U</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Genome Studies, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Dogan+OA%22">Dogan OA</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Genetics, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Akyoney+S%22">Akyoney S</searchLink>; Department of Bioinformatics and Biostatistic, Institute of Health Sciences, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Sayitoglu+M%22">Sayitoglu M</searchLink>; Department of Genetics, Istanbul University, Institute of Aziz Sancar Experimental Medicine, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Nordgren+A%22">Nordgren A</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Bugra+Agaoglu+N%22">Bugra Agaoglu N</searchLink>; Department of Cancer Genetics, Umraniye Traning and Research Hospital, Istanbul, Türkiye.; Department of Neurology, Krankenhaus Nordwest, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Ozbek+U%22">Ozbek U</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; International Biomedicine and Genome Institute (iBG), Izmir Dokuz Eylül University, Izmir, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ng+OH%22">Ng OH</searchLink>; Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Rare Diseases and Orphan Drugs Application and Research Center (ACURARE), Acıbadem University, Istanbul, Türkiye.; Department of Medical Biology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye.
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