Genomic and transcriptomic analyses of residual invasive triple-negative breast cancer after neoadjuvant chemotherapy in the prospective MIRINAE trial (a randomized phase II trial of adjuvant atezolizumab plus capecitabine compared to capecitabine; KCSG-BR18-21).

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Title: Genomic and transcriptomic analyses of residual invasive triple-negative breast cancer after neoadjuvant chemotherapy in the prospective MIRINAE trial (a randomized phase II trial of adjuvant atezolizumab plus capecitabine compared to capecitabine; KCSG-BR18-21).
Authors: Im SA; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Park K; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea., Koh J; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Park C; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Jung KH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee J; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Ahn HK; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea., Lee A; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, Catholic University, Seoul, Republic of Korea., Sim SH; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea., Kim MH; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim JH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim JH; Division of Medical Oncology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee KE; Department of Hematology and Oncology, Ewha Womans University Hospital, Seoul, Republic of Korea., Park KH; Division of Hemato-Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea., Bae J; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea., Lee MH; Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea., Lim S; Department of Hemato-Oncology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea., Kim HJ; Division of Oncology and Hematology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea., Lee DW; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Jeong JH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee KS; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea., Sohn J; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Suh KJ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim JY; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Cha YJ; Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Moon J; Lunit, Seoul, Republic of Korea., Ock CY; Lunit, Seoul, Republic of Korea., Kim SB; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Shin K; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Chae H; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim GM; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee KH; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Park WY; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea., Park YH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: yhparkhmo@skku.edu., Park IH; Division of Oncology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Republic of Korea. Electronic address: parkih@korea.ac.kr.
Corporate Authors: Korean Cancer Study Group (KCSG) Breast Cancer Committee
Source: ESMO open [ESMO Open] 2025 Oct; Vol. 10 (10), pp. 105804. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101690685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7029 (Electronic) Linking ISSN: 20597029 NLM ISO Abbreviation: ESMO Open Subsets: MEDLINE
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  Data: Genomic and transcriptomic analyses of residual invasive triple-negative breast cancer after neoadjuvant chemotherapy in the prospective MIRINAE trial (a randomized phase II trial of adjuvant atezolizumab plus capecitabine compared to capecitabine; KCSG-BR18-21).
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  Data: <searchLink fieldCode="AU" term="%22Im+SA%22">Im SA</searchLink>; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+K%22">Park K</searchLink>; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koh+J%22">Koh J</searchLink>; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+C%22">Park C</searchLink>; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+KH%22">Jung KH</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+HK%22">Ahn HK</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, Catholic University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sim+SH%22">Sim SH</searchLink>; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MH%22">Kim MH</searchLink>; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KE%22">Lee KE</searchLink>; Department of Hematology and Oncology, Ewha Womans University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+KH%22">Park KH</searchLink>; Division of Hemato-Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+J%22">Bae J</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MH%22">Lee MH</searchLink>; Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+S%22">Lim S</searchLink>; Department of Hemato-Oncology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Division of Oncology and Hematology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+DW%22">Lee DW</searchLink>; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+JH%22">Jeong JH</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KS%22">Lee KS</searchLink>; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+J%22">Sohn J</searchLink>; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Suh+KJ%22">Suh KJ</searchLink>; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JY%22">Kim JY</searchLink>; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cha+YJ%22">Cha YJ</searchLink>; Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+J%22">Moon J</searchLink>; Lunit, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ock+CY%22">Ock CY</searchLink>; Lunit, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SB%22">Kim SB</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+K%22">Shin K</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chae+H%22">Chae H</searchLink>; Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+GM%22">Kim GM</searchLink>; Division of Medical Oncology and Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+WY%22">Park WY</searchLink>; Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+YH%22">Park YH</searchLink>; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: yhparkhmo@skku.edu.<br /><searchLink fieldCode="AU" term="%22Park+IH%22">Park IH</searchLink>; Division of Oncology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Republic of Korea. Electronic address: parkih@korea.ac.kr.
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  Data: <searchLink fieldCode="CA" term="%22Korean+Cancer+Study+Group+%28KCSG%29+Breast+Cancer+Committee%22">Korean Cancer Study Group (KCSG) Breast Cancer Committee</searchLink>
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101690685 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-7029 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220597029%22">20597029 </searchLink><i>NLM ISO Abbreviation: </i>ESMO Open <i>Subsets: </i>MEDLINE
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