Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial.
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| Title: | Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial. |
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| Authors: | Kao D; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address: dkao@ualberta.ca., Wong K; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Lee C; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Island Medical Program, University of Victoria, BC, Canada., Steiner T; Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada., Franz R; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., McDougall C; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Silva M; Division of Infectious Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada., Schmidt TSB; School of Medicine, University College Cork, Cork, Munster, Ireland; APC Microbiome Ireland, University College Cork, Cork, Munster, Ireland., Walter J; School of Microbiology, Department of Medicine, University College Cork, Cork, Munster, Ireland; APC Microbiome Ireland, University College Cork, Cork, Munster, Ireland., Loebenberg R; Drug Development and Innovation Centre, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada., Monaghan TM; NIHR Nottingham Biomedical Research Center, Nottingham Digestive Disease Center, and Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK., Giebelhaus RT; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Harynuk JJ; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Xu H; Biostatistics & Health Data Science, School of Medicine, Indiana University, Indianapolis, IN, USA., Yaskina M; Women and Children's Health Research Institute, University of Alberta, Edmonton, AB, Canada., MacDonald KV; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Marshall DA; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Louie T; Division of Infectious Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada. |
| Source: | The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2025 Nov; Vol. 10 (11), pp. 986-997. Date of Electronic Publication: 2025 Sep 22. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial; Comparative Study |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40997843 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kao+D%22">Kao D</searchLink>; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address: dkao@ualberta.ca.<br /><searchLink fieldCode="AU" term="%22Wong+K%22">Wong K</searchLink>; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+C%22">Lee C</searchLink>; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Island Medical Program, University of Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Steiner+T%22">Steiner T</searchLink>; Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Franz+R%22">Franz R</searchLink>; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22McDougall+C%22">McDougall C</searchLink>; Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Silva+M%22">Silva M</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Schmidt+TSB%22">Schmidt TSB</searchLink>; School of Medicine, University College Cork, Cork, Munster, Ireland; APC Microbiome Ireland, University College Cork, Cork, Munster, Ireland.<br /><searchLink fieldCode="AU" term="%22Walter+J%22">Walter J</searchLink>; School of Microbiology, Department of Medicine, University College Cork, Cork, Munster, Ireland; APC Microbiome Ireland, University College Cork, Cork, Munster, Ireland.<br /><searchLink fieldCode="AU" term="%22Loebenberg+R%22">Loebenberg R</searchLink>; Drug Development and Innovation Centre, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Monaghan+TM%22">Monaghan TM</searchLink>; NIHR Nottingham Biomedical Research Center, Nottingham Digestive Disease Center, and Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Giebelhaus+RT%22">Giebelhaus RT</searchLink>; Department of Chemistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Harynuk+JJ%22">Harynuk JJ</searchLink>; Department of Chemistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Biostatistics & Health Data Science, School of Medicine, Indiana University, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Yaskina+M%22">Yaskina M</searchLink>; Women and Children's Health Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22MacDonald+KV%22">MacDonald KV</searchLink>; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Marshall+DA%22">Marshall DA</searchLink>; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Louie+T%22">Louie T</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101690683%22">The lancet. Gastroenterology & hepatology</searchLink> [Lancet Gastroenterol Hepatol] 2025 Nov; Vol. 10 (11), pp. 986-997. <i>Date of Electronic Publication: </i>2025 Sep 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial; Comparative Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101690683 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2468-1253 (Electronic) <i>NLM ISO Abbreviation: </i>Lancet Gastroenterol Hepatol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40997843 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S2468-1253(25)00190-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 986 Titles: – TitleFull: Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kao D – PersonEntity: Name: NameFull: Wong K – PersonEntity: Name: NameFull: Lee C – PersonEntity: Name: NameFull: Steiner T – PersonEntity: Name: NameFull: Franz R – PersonEntity: Name: NameFull: McDougall C – PersonEntity: Name: NameFull: Silva M – PersonEntity: Name: NameFull: Schmidt TSB – PersonEntity: Name: NameFull: Walter J – PersonEntity: Name: NameFull: Loebenberg R – PersonEntity: Name: NameFull: Monaghan TM – PersonEntity: Name: NameFull: Giebelhaus RT – PersonEntity: Name: NameFull: Harynuk JJ – PersonEntity: Name: NameFull: Xu H – PersonEntity: Name: NameFull: Yaskina M – PersonEntity: Name: NameFull: MacDonald KV – PersonEntity: Name: NameFull: Marshall DA – PersonEntity: Name: NameFull: Louie T IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2025 Nov Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2468-1253 Numbering: – Type: volume Value: 10 – Type: issue Value: 11 Titles: – TitleFull: The lancet. Gastroenterology & hepatology Type: main |
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