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Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy.

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Title: Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy.
Authors: Chen XL; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Tharp KM; Sanford Burnham Prebys Discovery Institute, Cancer Metabolism and Microenvironment Program, La Jolla, CA., Ojalill M; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Ozmadenci D; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Boyer A; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Hannen Iii TJ; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Lawson C; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Lee HJ; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Xia M; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Tahon E; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Zhang Y; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Minor C; Sanford Burnham Prebys Discovery Institute, Cancer Metabolism and Microenvironment Program, La Jolla, CA., Khan SU; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Anderson CC; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Rose M; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA., Estrada MV; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA., Molinolo AA; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA., Warren E; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA., Penolosa P; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Eskander RN; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., McHale MT; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Wang SE; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA., Connolly DC; Fox Chase Cancer Center, Cancer Signaling and Microenvironment Program, Philadelphia, PA., Fisch KM; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Maternal and Fetal Medicine, La Jolla, CA., Stupack DG; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA., Schlaepfer DD; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 17. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Chen+XL%22">Chen XL</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Tharp+KM%22">Tharp KM</searchLink>; Sanford Burnham Prebys Discovery Institute, Cancer Metabolism and Microenvironment Program, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Ojalill+M%22">Ojalill M</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Ozmadenci+D%22">Ozmadenci D</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Boyer+A%22">Boyer A</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Hannen+Iii+TJ%22">Hannen Iii TJ</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Lawson+C%22">Lawson C</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Lee+HJ%22">Lee HJ</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Xia+M%22">Xia M</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Tahon+E%22">Tahon E</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Minor+C%22">Minor C</searchLink>; Sanford Burnham Prebys Discovery Institute, Cancer Metabolism and Microenvironment Program, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Khan+SU%22">Khan SU</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Anderson+CC%22">Anderson CC</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Nemkov+T%22">Nemkov T</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Rose+M%22">Rose M</searchLink>; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Estrada+MV%22">Estrada MV</searchLink>; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Molinolo+AA%22">Molinolo AA</searchLink>; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Warren+E%22">Warren E</searchLink>; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Penolosa+P%22">Penolosa P</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Eskander+RN%22">Eskander RN</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22McHale+MT%22">McHale MT</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Wang+SE%22">Wang SE</searchLink>; University of California San Diego, Department of Pathology, Moores Cancer Center, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Connolly+DC%22">Connolly DC</searchLink>; Fox Chase Cancer Center, Cancer Signaling and Microenvironment Program, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Fisch+KM%22">Fisch KM</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Maternal and Fetal Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Stupack+DG%22">Stupack DG</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Schlaepfer+DD%22">Schlaepfer DD</searchLink>; University of California San Diego, Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores Cancer Center, Division of Gynecologic Oncology, La Jolla, CA.
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