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Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.

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Title: Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.
Authors: Vujkovic M; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Kaplan DE; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ghouse J; The Heart Centre, Laboratory for Molecular Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark., Loza BL; Department of Surgery, Penn Transplant Institute, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA., Brancale J; Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA.; Departments of Genetics and Pathology, Yale School of Medicine, New Haven, CT, USA., Lewis A; Department of Biomedical Informatics, Center for Precision Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Zhang DY; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Levin MG; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Veatch OJ; Department of Psychiatry and Behavioral Sciences, Division of Medical Informatics, University of Kansas Medical Center, Kansas City, KA, USA., Johnson JP; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Schneider CV; Department of Medicine III, Gastroenterology, Metabolic Diseases, and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany.; German Cancer Research Center (DKFZ), Dresden, Germany.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Verma A; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Wangensteen KJ; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Scorletti E; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Konkwo C; Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA., Garófalo AM; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Guare LA; Department of Medicine, Division of Pathology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Schwantes-An TW; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; VA Long Beach Healthcare System, Long Beach, CA, USA., Abreu MV; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; VA Long Beach Healthcare System, Long Beach, CA, USA., Gellert-Kristensen H; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Pedersen OB; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Bundgaard JS; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Sørensen E; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ostrowski SR; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Bundgaard H; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Lee KM; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA., Shaked A; Department of Surgery, Penn Transplant Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Olthoff KM; Department of Surgery, Penn Transplant Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Hoteit MA; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Speliotes EK; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA.; The Gilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Chen Y; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA., Oliveri A; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA., Yin L; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA., Valenti LV; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Precision Medicine and Biological Resource Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy., Malvestiti F; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Marchelli D; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Miano L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Precision Medicine and Biological Resource Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy., Anstee QM; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK., Daly AK; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Cordell HJ; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Darlay R; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Verweij N; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Hindy G; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Locke A; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Matsuura K; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Asrani SK; Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX, USA., Testa G; Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX, USA., Lotta LA; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Jones MB; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Dochtermann DR; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., Norden-Krichmar TM; VA Long Beach Healthcare System, Long Beach, CA, USA.; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA., Teerlink CC; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, USA., Devineni P; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., Pyarajan S; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard School of Medicine, Boston, MA, USA., Rader DJ; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Tanaka Y; Faculty of Life Sciences, Department of Gastroenterology and Hepatology, Kumamoto University, Kumamoto, Japan., Voight BF; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Vilarinho S; Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA.; Departments of Genetics and Pathology, Yale School of Medicine, New Haven, CT, USA., Bastarache LA; Department of Biomedical Informatics, Center for Precision Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Stender S; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Tsao PS; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Morgan TR; VA Long Beach Healthcare System, Long Beach, CA, USA.; Department of Medicine, University of California, Irvine, CA, USA., Lynch JA; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, USA., Chang KM; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Corporate Authors: Penn Medicine Biobank, DBDS Genomic Consortium, BioVU Biobank, Michigan Genomics Initiative, Regeneron Genetics Center, Indiana Biobank, All Of Us Research Program, Milano Biobank, LITMUS Consortium, VA Million Veteran Program
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Sep 18. Date of Electronic Publication: 2025 Sep 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.
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  Data: <searchLink fieldCode="AU" term="%22Vujkovic+M%22">Vujkovic M</searchLink>; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kaplan+DE%22">Kaplan DE</searchLink>; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ghouse+J%22">Ghouse J</searchLink>; The Heart Centre, Laboratory for Molecular Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Loza+BL%22">Loza BL</searchLink>; Department of Surgery, Penn Transplant Institute, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brancale+J%22">Brancale J</searchLink>; Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA.; Departments of Genetics and Pathology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+A%22">Lewis A</searchLink>; Department of Biomedical Informatics, Center for Precision Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+DY%22">Zhang DY</searchLink>; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Levin+MG%22">Levin MG</searchLink>; Corporal Michael J. 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Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+CV%22">Schneider CV</searchLink>; Department of Medicine III, Gastroenterology, Metabolic Diseases, and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany.; German Cancer Research Center (DKFZ), Dresden, Germany.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Verma+A%22">Verma A</searchLink>; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wangensteen+KJ%22">Wangensteen KJ</searchLink>; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Scorletti+E%22">Scorletti E</searchLink>; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gill+D%22">Gill D</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Konkwo+C%22">Konkwo C</searchLink>; Department of Internal Medicine, Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Garófalo+AM%22">Garófalo AM</searchLink>; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Guare+LA%22">Guare LA</searchLink>; Department of Medicine, Division of Pathology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schwantes-An+TW%22">Schwantes-An TW</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; VA Long Beach Healthcare System, Long Beach, CA, USA.<br /><searchLink fieldCode="AU" term="%22Abreu+MV%22">Abreu MV</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; VA Long Beach Healthcare System, Long Beach, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gellert-Kristensen+H%22">Gellert-Kristensen H</searchLink>; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+OB%22">Pedersen OB</searchLink>; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Erikstrup+C%22">Erikstrup C</searchLink>; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bundgaard+JS%22">Bundgaard JS</searchLink>; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sørensen+E%22">Sørensen E</searchLink>; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ostrowski+SR%22">Ostrowski SR</searchLink>; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bundgaard+H%22">Bundgaard H</searchLink>; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lee+KM%22">Lee KM</searchLink>; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Shaked+A%22">Shaked A</searchLink>; Department of Surgery, Penn Transplant Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Olthoff+KM%22">Olthoff KM</searchLink>; Department of Surgery, Penn Transplant Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hoteit+MA%22">Hoteit MA</searchLink>; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Speliotes+EK%22">Speliotes EK</searchLink>; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA.; The Gilbert S. 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Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marchelli+D%22">Marchelli D</searchLink>; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Miano+L%22">Miano L</searchLink>; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Precision Medicine and Biological Resource Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Anstee+QM%22">Anstee QM</searchLink>; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Daly+AK%22">Daly AK</searchLink>; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Cordell+HJ%22">Cordell HJ</searchLink>; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Darlay+R%22">Darlay R</searchLink>; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Verweij+N%22">Verweij N</searchLink>; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hindy+G%22">Hindy G</searchLink>; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Locke+A%22">Locke A</searchLink>; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Matsuura+K%22">Matsuura K</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Asrani+SK%22">Asrani SK</searchLink>; Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Testa+G%22">Testa G</searchLink>; Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lotta+LA%22">Lotta LA</searchLink>; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jones+MB%22">Jones MB</searchLink>; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dochtermann+DR%22">Dochtermann DR</searchLink>; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Norden-Krichmar+TM%22">Norden-Krichmar TM</searchLink>; VA Long Beach Healthcare System, Long Beach, CA, USA.; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Teerlink+CC%22">Teerlink CC</searchLink>; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Devineni+P%22">Devineni P</searchLink>; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pyarajan+S%22">Pyarajan S</searchLink>; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rader+DJ%22">Rader DJ</searchLink>; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; 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Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2025 Sep 18. <i>Date of Electronic Publication: </i>2025 Sep 18.
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      – TitleFull: Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.
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      – PersonEntity:
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          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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    IsPartOfRelationships:
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          Dates:
            – D: 18
              M: 09
              Text: 2025 Sep 18
              Type: published
              Y: 2025
          Titles:
            – TitleFull: MedRxiv : the preprint server for health sciences
              Type: main
ResultId 1