Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay.
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| Title: | Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay. |
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| Authors: | Waweru G; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; School of Pure and Applied Sciences, Department of Biological Sciences, Pwani University, Kilifi P.O. Box 195-80108, Kenya., Nyakundi R; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya., Kutima B; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Owuor S; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Konyino G; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Gitonga J; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Lugano D; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Maina A; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Musyoki J; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Ochola L; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya., Omondi M; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya., Kariuki CK; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya., Ogongo P; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya., Mwachari C; Kenya Medical Research Institute, Nairobi P.O. Box 54840 00200, Kenya., Shee F; School of Pure and Applied Sciences, Department of Biological Sciences, Pwani University, Kilifi P.O. Box 195-80108, Kenya., Agoti C; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Sande C; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Uyoga S; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Kagucia E; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Agweyu A; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Bejon P; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Nuffield Department of Medicine, Oxford University, Oxford OX3 7BN, UK., Scott JAG; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Warimwe GM; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Nuffield Department of Medicine, Oxford University, Oxford OX3 7BN, UK., Ochola-Oyier LI; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya., Nyagwange J; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya. |
| Source: | Viruses [Viruses] 2025 Sep 16; Vol. 17 (9). Date of Electronic Publication: 2025 Sep 16. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41012675 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Waweru+G%22">Waweru G</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; School of Pure and Applied Sciences, Department of Biological Sciences, Pwani University, Kilifi P.O. Box 195-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Nyakundi+R%22">Nyakundi R</searchLink>; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya.<br /><searchLink fieldCode="AU" term="%22Kutima+B%22">Kutima B</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Owuor+S%22">Owuor S</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Konyino+G%22">Konyino G</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Gitonga+J%22">Gitonga J</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Lugano+D%22">Lugano D</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Maina+A%22">Maina A</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Musyoki+J%22">Musyoki J</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Ochola+L%22">Ochola L</searchLink>; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya.<br /><searchLink fieldCode="AU" term="%22Omondi+M%22">Omondi M</searchLink>; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya.<br /><searchLink fieldCode="AU" term="%22Kariuki+CK%22">Kariuki CK</searchLink>; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya.<br /><searchLink fieldCode="AU" term="%22Ogongo+P%22">Ogongo P</searchLink>; Kenya Institute of Primate Research, Nairobi P.O. Box 24481 00502, Kenya.<br /><searchLink fieldCode="AU" term="%22Mwachari+C%22">Mwachari C</searchLink>; Kenya Medical Research Institute, Nairobi P.O. Box 54840 00200, Kenya.<br /><searchLink fieldCode="AU" term="%22Shee+F%22">Shee F</searchLink>; School of Pure and Applied Sciences, Department of Biological Sciences, Pwani University, Kilifi P.O. Box 195-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Agoti+C%22">Agoti C</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Sande+C%22">Sande C</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Uyoga+S%22">Uyoga S</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Kagucia+E%22">Kagucia E</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Agweyu+A%22">Agweyu A</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.<br /><searchLink fieldCode="AU" term="%22Bejon+P%22">Bejon P</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Nuffield Department of Medicine, Oxford University, Oxford OX3 7BN, UK.<br /><searchLink fieldCode="AU" term="%22Scott+JAG%22">Scott JAG</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.<br /><searchLink fieldCode="AU" term="%22Warimwe+GM%22">Warimwe GM</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.; Nuffield Department of Medicine, Oxford University, Oxford OX3 7BN, UK.<br /><searchLink fieldCode="AU" term="%22Ochola-Oyier+LI%22">Ochola-Oyier LI</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya.<br /><searchLink fieldCode="AU" term="%22Nyagwange+J%22">Nyagwange J</searchLink>; KEMRI-Wellcome Trust Research Programme, Center for Geographic Medicine Research, Coast, Kilifi P.O. Box 230-80108, Kenya. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101509722%22">Viruses</searchLink> [Viruses] 2025 Sep 16; Vol. 17 (9). <i>Date of Electronic Publication: </i>2025 Sep 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Comparative Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101509722 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1999-4915 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994915%22">19994915 </searchLink><i>NLM ISO Abbreviation: </i>Viruses <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41012675 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/v17091248 Languages: – Code: eng Text: English Titles: – TitleFull: Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Waweru G – PersonEntity: Name: NameFull: Nyakundi R – PersonEntity: Name: NameFull: Kutima B – PersonEntity: Name: NameFull: Owuor S – PersonEntity: Name: NameFull: Konyino G – PersonEntity: Name: NameFull: Gitonga J – PersonEntity: Name: NameFull: Lugano D – PersonEntity: Name: NameFull: Maina A – PersonEntity: Name: NameFull: Musyoki J – PersonEntity: Name: NameFull: Ochola L – PersonEntity: Name: NameFull: Omondi M – PersonEntity: Name: NameFull: Kariuki CK – PersonEntity: Name: NameFull: Ogongo P – PersonEntity: Name: NameFull: Mwachari C – PersonEntity: Name: NameFull: Shee F – PersonEntity: Name: NameFull: Agoti C – PersonEntity: Name: NameFull: Sande C – PersonEntity: Name: NameFull: Uyoga S – PersonEntity: Name: NameFull: Kagucia E – PersonEntity: Name: NameFull: Agweyu A – PersonEntity: Name: NameFull: Bejon P – PersonEntity: Name: NameFull: Scott JAG – PersonEntity: Name: NameFull: Warimwe GM – PersonEntity: Name: NameFull: Ochola-Oyier LI – PersonEntity: Name: NameFull: Nyagwange J IsPartOfRelationships: – BibEntity: Dates: – D: 16 M: 09 Text: 2025 Sep 16 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1999-4915 Numbering: – Type: volume Value: 17 – Type: issue Value: 9 Titles: – TitleFull: Viruses Type: main |
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