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Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits.

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Title: Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits.
Authors: Han Y; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA.; Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico, USA.; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Shaw VR; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA., Byun J; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA.; Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico, USA.; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Thrift AP; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Zhu C; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA., Li D; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hatia RI; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Kelley RK; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA., Cleary SP; Division of Hepatobiliary & Pancreatic Surgery, University of Toronto, Toronto, Ontario, Canada., Lok AS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Bracci PM; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA., Permuth JB; Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, Florida, USA.; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Bucur R; University Health Network, Princess Margaret Cancer Center and Toronto General Hospital, Toronto, Ontario, Canada., Knox J; University Health Network, Princess Margaret Cancer Center and Toronto General Hospital, Toronto, Ontario, Canada., Yuan JM; Cancer Epidemiology and Prevention Program, UPMC Hillman Cancer Center, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Singal AG; Division of Digestive and Liver Diseases, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Jalal PK; Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA., Ghobrial RM; J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, Texas, USA., Kono Y; Division of Gastroenterology & Hepatology, University of California San Diego, San Diego, California, USA., Shah DP; Mays Cancer Center, The University of Texas Health Science Center San Antonio MD Anderson, San Antonio, Texas, USA., Nguyen MH; Division of Gastroenterology and Hepatology, Department of Epidemiology and Population Health, Stanford University Medical Center, Palo Alto, California, USA., Parikh ND; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Kim R; Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, Florida, USA., Wu HC; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York City, New York, USA., El-Serag H; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Chang P; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA., Chun YS; Division of Surgery, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gu J; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Huff C; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Rashid A; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hwang LY; Department of Epidemiology, Human Genetics, and Environment Science, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Klein AP; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA., Khaderi SA; Division of Abdominal Transplantation, Baylor College of Medicine, Houston, Texas, USA., Kaseb AO; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., McGlynn KA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Roberts LR; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Hassan MM; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Amos CI; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA.; Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico, USA.; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Source: International journal of cancer [Int J Cancer] 2026 Mar 01; Vol. 158 (5), pp. 1193-1203. Date of Electronic Publication: 2025 Sep 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
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  Data: Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits.
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