Loganin, an Iridoid Glycoside, Alleviates Paclitaxel-Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence.

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Title: Loganin, an Iridoid Glycoside, Alleviates Paclitaxel-Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence.
Authors: Chuang YF; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Wu CR; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Chang WH; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Su YJ; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Hsu HT; Department of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Anesthesiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Lin FL; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; School of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan., Lo YC; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Traditional Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Precision Sports Medicine and Health Promotion Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Source: The Kaohsiung journal of medical sciences [Kaohsiung J Med Sci] 2026 Apr; Vol. 42 (4), pp. e70117. Date of Electronic Publication: 2025 Sep 27.
Publication Type: Journal Article
Journal Info: Publisher: Department of Public Health, Kaohsiung Medical University Country of Publication: China (Republic : 1949- ) NLM ID: 100960562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2410-8650 (Electronic) Linking ISSN: 1607551X NLM ISO Abbreviation: Kaohsiung J Med Sci Subsets: MEDLINE
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  Data: Loganin, an Iridoid Glycoside, Alleviates Paclitaxel-Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence.
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  Data: <searchLink fieldCode="AU" term="%22Chuang+YF%22">Chuang YF</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CR%22">Wu CR</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+WH%22">Chang WH</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+YJ%22">Su YJ</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+HT%22">Hsu HT</searchLink>; Department of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Anesthesiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+FL%22">Lin FL</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; School of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lo+YC%22">Lo YC</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Traditional Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Precision Sports Medicine and Health Promotion Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22100960562%22">The Kaohsiung journal of medical sciences</searchLink> [Kaohsiung J Med Sci] 2026 Apr; Vol. 42 (4), pp. e70117. <i>Date of Electronic Publication: </i>2025 Sep 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Department+of+Public+Health%2C+Kaohsiung+Medical+University%22">Department of Public Health, Kaohsiung Medical University </searchLink><i>Country of Publication: </i>China (Republic : 1949- ) <i>NLM ID: </i>100960562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2410-8650 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221607551X%22">1607551X </searchLink><i>NLM ISO Abbreviation: </i>Kaohsiung J Med Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1002/kjm2.70117
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              Text: 2026 Apr
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