Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study.
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| Title: | Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study. |
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| Authors: | Chalitsios CV; Department of Hygiene and Epidemiology, University of Ioannina, Ioannina, Greece., Markozannes G; Department of Hygiene and Epidemiology, University of Ioannina, Ioannina, Greece.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Aglago EK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States., Buchanan DD; Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia.; Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia., Campbell PT; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, United States., Cao Y; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO, United States.; Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St Louis, MO, United States.; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St Louis, MO, United States., Chan AT; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.; Broad Institute of Harvard and MIT, Cambridge, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States., Dimou N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Drew DA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States., French AJ; Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States., Georgeson P; Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia., Giannakis M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Gruber SB; Department of Medical Oncology and Therapeutics Research and Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, United States., Gunter MJ; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Harrison TA; Public Health Sciences Division, Seattle, WA, United States., Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg, Germany., Hsu L; Public Health Sciences Division, Seattle, WA, United States.; Department of Biostatistics, University of Washington, Seattle, WA, United States., Huang WY; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States., Hullar MAJ; Public Health Sciences Division, Seattle, WA, United States., Huyghe JR; Public Health Sciences Division, Seattle, WA, United States., Lynch BM; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia., Moreno V; Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet del Llobregat, Barcelona, Spain.; ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and health Sciences and Universitat de Barcelona Institute of Complex Systems, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain., Murphy N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Newton CC; Department of Population Science, American Cancer Society, Atlanta, GA, United States., Nowak JA; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Obón-Santacana M; Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet del Llobregat, Barcelona, Spain.; ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and health Sciences and Universitat de Barcelona Institute of Complex Systems, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain., Ogino S; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Tokyo Medical and Dental University (Institute of Science Tokyo), Tokyo, Japan., Qu C; Public Health Sciences Division, Seattle, WA, United States., Schmit SL; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, United States.; Population and Cancer Prevention Program, Case Comprehensive Cancer Center, Cleveland, OH, United States., Steinfelder RS; Public Health Sciences Division, Seattle, WA, United States., Sun W; Public Health Sciences Division, Seattle, WA, United States., Thomas CE; Public Health Sciences Division, Seattle, WA, United States., Toland AE; Departments of Cancer Biology and Genetics, The Ohio State University, Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, United States., Trinh QM; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Ugai T; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States., Um CY; Department of Population Science, American Cancer Society, Atlanta, GA, United States., Guelpen BV; Department of Diagnostics and Intervention, Oncology Unit, Umeå University, Umeå, Sweden.; Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden., Zaidi SH; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Schoen RE; Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, United States., Woods MO; Discipline of Genetics, Memorial University of Newfoundland, St John's, Canada., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg, Germany.; German Cancer Consortium (Deutsches Konsortium für Translationale Krebsforschung, DKTK), German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg, Germany., Andreson L; Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Pellatt AJ; Intermountain Health, Salt Lake City, UT, United States., Peters U; Public Health Sciences Division, Seattle, WA, United States.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, United States., Phipps AI; Public Health Sciences Division, Seattle, WA, United States.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, United States., Tsilidis KK; Department of Hygiene and Epidemiology, University of Ioannina, Ioannina, Greece.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom. |
| Source: | JNCI cancer spectrum [JNCI Cancer Spectr] 2025 Nov 03; Vol. 9 (6). |
| Publication Type: | Journal Article; Observational Study |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101721827 Publication Model: Print Cited Medium: Internet ISSN: 2515-5091 (Electronic) Linking ISSN: 25155091 NLM ISO Abbreviation: JNCI Cancer Spectr Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2515-5091 |
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| DOI: | 10.1093/jncics/pkaf095 |
