KRAS-induced STN1 (OBFC1) promotes proper CTC1-STN1-TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer.

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Title: KRAS-induced STN1 (OBFC1) promotes proper CTC1-STN1-TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer.
Authors: Shen C; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States., Cui T; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States., Yang L; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States., Gui L; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, China., Corrales-Guerrero S; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States., Nair S; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States., Li H; Integrative Genomic Core, Beckman Research Institute of City of Hope, Duarte, 91010, United States., Karasinska JM; Pancreas Centre BC, BC Cancer Research Centre, Vancouver, BC, V5Z 0B4, Canada., Topham JT; Pancreas Centre BC, BC Cancer Research Centre, Vancouver, BC, V5Z 0B4, Canada., Renouf DJ; Pancreas Centre BC, BC Cancer Research Centre, Vancouver, BC, V5Z 0B4, Canada., Schaeffer DF; Pancreas Centre BC, BC Cancer Research Centre, Vancouver, BC, V5Z 0B4, Canada., Fernandez A; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, 91010, United States., Ping X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, 91010, United States., Shen B; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, 91010, United States., Stark JM; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, 91010, United States., Williams TM; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, 91010, United States.
Source: Nucleic acids research [Nucleic Acids Res] 2025 Sep 23; Vol. 53 (18).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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