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Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites.

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Title: Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites.
Authors: Ebrahimi E; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.; Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran., Sangphukieo A; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.; Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Park HA; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Gaborieau V; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Ferreiro-Iglesias A; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Diergaarde B; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, USA.; UPMC Hillman Cancer Center, Pittsburgh, USA., Ahrens W; Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany., Alemany L; Catalan Institute of Oncology. ICO, L'Hospitalet, Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Spain.; CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Arantes LM; Barretos Cancer Hospital, Barretos, Brazil., Betka J; Department of Otorhinolarygology and Head And Neck Surgery, 1.st Medical Faculty, Charles University, Faculty Hospital Motol, Prague, Czech Republic., Bratman SV; Depts of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada., Canova C; Unit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padova, Padova, Italy., Conlon MS; Epidemiology, Outcomes & Evaluation Research, Health Sciences North Research Institute, Sudbury, Canada., Conway DI; School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK., Cuello M; Oncology, Hospital de Clinicas Dr. Manuel Quintela, Montevideo, Uruguay., Curado MP; Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center, São Paulo, Brazil., de Carvalho AC; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., de Oliviera JC; Araújo Jorge Cancer Hospital, Associação de Combate ao Câncer em Goiás, Goiania, Brazil., Gormley M; Bristol Dental School, Bristol University, Bristol, UK., Hadji M; Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Hargreaves S; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK., Healy CM; School of Dental Science, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland., Holcatova I; Institute of Hygiene & Epidemiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Hung RJ; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., Kowalski LP; Department of Head and Neck Surgery, University of São Paulo Medical School, São Paulo, Brazil.; Department of Head and Neck Surgery and Otorhinolaryngology, A C Camargo Cancer Center, São Paulo, Brazil., Lagiou P; Department of Hygiene, Epidemiology & Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Lagiou A; Department of Public and Community Health, School of Public Health, University of West Attica, Athens, Greece., Liu G; Medicine, Epidemiology, Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada., Macfarlane GJ; Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, USA., Perdomo S; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Pinto LFR; Programa de Carcinogênese Molecular, Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil., Podesta JRV; Head and Neck Surgery Division, Women's Association for Education and Fight Against Cancer/AFECC, Vitória, Brazil., Polesel J; Unit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy., Pring M; Bristol Dental School, Bristol University, Bristol, UK., Rashidian H; Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran., Gama RR; Department of Head and Neck Surgery, Barretos Cancer Hospital, São Paulo, Brazil., Richiardi L; Cancer Epidemiology Unit, University of Turin, Turin, Italy., Robinson M; Cellular Pathology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Rodriguez-Urrego PA; Pathology and Laboratories, Pathology, University Hospital Fundacion Santa Fe de Bogota, Bogota, Colombia., Santi SA; Clinical Oncology Research, Health Sciences North Research Institute, Sudbury, Canada., Saunders DP; Department of Dental Oncology, Health Sciences North, Northern Ontario School of Medicine University, Sudbury, Canada., Soares-Lima SC; Brazilian National Cancer Institute, Rio de Janeiro, Brazil., Timpson N; MRC Integrative Epidemiology Unit, Bristol University, Bristol, UK., Vilensky M; Instituto de Oncologia Angel H Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina., von Zeidler SV; Pathology Department, Federal University of Espírito Santo, Vitória, Brazil., Waterboer T; Infections and Cancer Epidemiology, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), Heidelberg, Germany., Zendehdel K; Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran., Znaor A; Cancer Surveillance Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Brennan P; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., McKay J; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Virani S; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France. viranis@iarc.who.int., Dudding T; Bristol Dental School, Bristol University, Bristol, UK. tom.dudding@bristol.ac.uk.
Corporate Authors: HEADSpAcE Consortium
Source: Nature communications [Nat Commun] 2025 Oct 02; Vol. 16 (1), pp. 8787. Date of Electronic Publication: 2025 Oct 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-63842-z