Subcutaneous daratumumab plus carfilzomib and dexamethasone (D-Kd) versus carfilzomib and dexamethasone (Kd) in patients with relapsed/refractory multiple myeloma who received previous daratumumab treatment: LYNX study.

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Title: Subcutaneous daratumumab plus carfilzomib and dexamethasone (D-Kd) versus carfilzomib and dexamethasone (Kd) in patients with relapsed/refractory multiple myeloma who received previous daratumumab treatment: LYNX study.
Authors: Bahlis NJ; Arnie Charbonneau Cancer Research Institute, University of Calgary, Calgary, Canada., Zonder J; Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA., Karlin L; Department of Hematology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France., Plesner T; Vejle Hospital, University of Southern Denmark, Vejle, Denmark., Paris L; Division of Hematology, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy., Wrobel T; Uniwersytet Medyczny we Wrocławiu, Wroclaw, Poland., Hungria V; Clínica Medica São Germano, São Paulo, Brazil., Besemer B; Abteilung für Innere Medizin II, Universitätsklinikum Tübingen der Eberhard-Karls-Universität, Tübingen, Germany., Crusoe E; Hospital São Rafael, Instituto D'Or de Pesquisa e Ensino and Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia-HUPES-UFBA, Salvador, Brazil., Silkjaer T; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark., Perrot A; Université de Toulouse, CHU de Toulouse, Service d'Hématologie, Toulouse, France., Moreau P; Hematology Department, University Hospital Hôtel-Dieu, Nantes, France., Wu KL; ZNA Stuivenberg, Antwerp, Belgium., Delimpasi S; Evangelismos Hospital, Athens, Greece., Dimopoulos MA; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.; Department of Medicine, Korea University, Seoul, South Korea., Levin MD; Albert Schweitzer Hospital, Dordrecht, The Netherlands., Mangiacavalli S; Division of Hematology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy., Nnane I; Johnson & Johnson, Washington, PA, USA., Kim YJ; Johnson & Johnson, Raritan, NJ, USA., Krevvata M; Johnson & Johnson, Washington, PA, USA., Sha L; Johnson & Johnson, Shanghai, China., Wroblewski S; Johnson & Johnson, Washington, PA, USA., Tuozzo A; Johnson & Johnson, Washington, PA, USA., Carson R; Johnson & Johnson, Washington, PA, USA., Facon T; University of Lille, CHU Lille, Lille, France.
Source: Leukemia & lymphoma [Leuk Lymphoma] 2025 Dec; Vol. 66 (14), pp. 2685-2696. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Subcutaneous daratumumab plus carfilzomib and dexamethasone (D-Kd) versus carfilzomib and dexamethasone (Kd) in patients with relapsed/refractory multiple myeloma who received previous daratumumab treatment: LYNX study.
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  Data: <searchLink fieldCode="AU" term="%22Bahlis+NJ%22">Bahlis NJ</searchLink>; Arnie Charbonneau Cancer Research Institute, University of Calgary, Calgary, Canada.<br /><searchLink fieldCode="AU" term="%22Zonder+J%22">Zonder J</searchLink>; Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Karlin+L%22">Karlin L</searchLink>; Department of Hematology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.<br /><searchLink fieldCode="AU" term="%22Plesner+T%22">Plesner T</searchLink>; Vejle Hospital, University of Southern Denmark, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Paris+L%22">Paris L</searchLink>; Division of Hematology, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Wrobel+T%22">Wrobel T</searchLink>; Uniwersytet Medyczny we Wrocławiu, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Hungria+V%22">Hungria V</searchLink>; Clínica Medica São Germano, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Besemer+B%22">Besemer B</searchLink>; Abteilung für Innere Medizin II, Universitätsklinikum Tübingen der Eberhard-Karls-Universität, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Crusoe+E%22">Crusoe E</searchLink>; Hospital São Rafael, Instituto D'Or de Pesquisa e Ensino and Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia-HUPES-UFBA, Salvador, Brazil.<br /><searchLink fieldCode="AU" term="%22Silkjaer+T%22">Silkjaer T</searchLink>; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Perrot+A%22">Perrot A</searchLink>; Université de Toulouse, CHU de Toulouse, Service d'Hématologie, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Moreau+P%22">Moreau P</searchLink>; Hematology Department, University Hospital Hôtel-Dieu, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Wu+KL%22">Wu KL</searchLink>; ZNA Stuivenberg, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Delimpasi+S%22">Delimpasi S</searchLink>; Evangelismos Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Dimopoulos+MA%22">Dimopoulos MA</searchLink>; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.; Department of Medicine, Korea University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Levin+MD%22">Levin MD</searchLink>; Albert Schweitzer Hospital, Dordrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mangiacavalli+S%22">Mangiacavalli S</searchLink>; Division of Hematology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Nnane+I%22">Nnane I</searchLink>; Johnson & Johnson, Washington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YJ%22">Kim YJ</searchLink>; Johnson & Johnson, Raritan, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Krevvata+M%22">Krevvata M</searchLink>; Johnson & Johnson, Washington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sha+L%22">Sha L</searchLink>; Johnson & Johnson, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wroblewski+S%22">Wroblewski S</searchLink>; Johnson & Johnson, Washington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tuozzo+A%22">Tuozzo A</searchLink>; Johnson & Johnson, Washington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Carson+R%22">Carson R</searchLink>; Johnson & Johnson, Washington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Facon+T%22">Facon T</searchLink>; University of Lille, CHU Lille, Lille, France.
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  Data: <searchLink fieldCode="JN" term="%229007422%22">Leukemia & lymphoma</searchLink> [Leuk Lymphoma] 2025 Dec; Vol. 66 (14), pp. 2685-2696. <i>Date of Electronic Publication: </i>2025 Oct 03.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9007422 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1029-2403 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210268022%22">10268022 </searchLink><i>NLM ISO Abbreviation: </i>Leuk Lymphoma <i>Subsets: </i>MEDLINE
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