Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model.
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| Title: | Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model. |
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| Authors: | Goya-Maldonado R; Laboratory of Systems Neuroscience and Imaging in Psychiatry (SNIP-Lab), Department of Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Georg-August University, Göttingen, Germany. roberto.goya@med.uni-goettingen.de., Erwin-Grabner T; Laboratory of Systems Neuroscience and Imaging in Psychiatry (SNIP-Lab), Department of Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Georg-August University, Göttingen, Germany., Zeng LL; College of Intelligence Science and Technology, National University of Defense Technology, Changsha, 410073, China.; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, 90274, USA., Ching CRK; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, 90274, USA., Aleman A; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Amod AR; Department of Psychiatry & Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Basgoze Z; Department of Psychiatry and Behavioral Science, University of Minnesota Medical School, Minneapolis, MN, USA., Benedetti F; Division of Neuroscience, IRCCS Scientific Institute Ospedale San Raffaele, Milano, Italy., Besteher B; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Brosch K; Department of Psychiatry and Psychotherapy, University of Marburg, Rudolf Bultmann Str. 8, 35039, Marburg, Germany., Bülow R; Institute for Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Colle R; MOODS Team, CESP, INSERM U1018, Faculté de Médecine, Univ Paris-Saclay, Le Kremlin Bicêtre, 94275, France.; Service Hospitalo-Universitaire de Psychiatrie de Bicêtre, Hôpitaux Universitaires Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Le Kremlin Bicêtre, F-94275, France., Connolly CG; Department of Biomedical Sciences, Florida State University, Tallahassee, FL, USA., Corruble E; MOODS Team, CESP, INSERM U1018, Faculté de Médecine, Univ Paris-Saclay, Le Kremlin Bicêtre, 94275, France.; Service Hospitalo-Universitaire de Psychiatrie de Bicêtre, Hôpitaux Universitaires Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Le Kremlin Bicêtre, F-94275, France., Couvy-Duchesne B; Sorbonne University, Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié Salpêtrière, F-75013, Paris, France.; Institute for Molecular Bioscience, the University of Queensland, St Lucia, QLD, Australia., Cullen K; Department of Psychiatry and Behavioral Science, University of Minnesota Medical School, Minneapolis, MN, USA., Dannlowski U; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Davey CG; Melbourne Neuropsychiatry Centre, Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia., Dols A; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; Department of Psychiatry, UMC Utrecht Brain Center, University Utrecht, Utrecht, the Netherlands., Ernsting J; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Evans JW; Experimental Therapeutics and Pathophysiology Branch, National Institute for Mental Health, National Institutes of Health, Bethesda, MD, USA., Fisch L; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Fuentes-Claramonte P; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Catalonia, Spain., Gonul AS; SoCAT Lab, Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey., Gotlib IH; Department of Psychology, Stanford University, Stanford, CA, USA., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Groenewold NA; Department of Psychiatry & Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Grotegerd D; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Hahn T; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Hamilton JP; Center for Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Han LKM; Centre for Youth Mental Health, the University of Melbourne, Parkville, VIC, Australia.; Orygen, Parkville, VIC, Australia., Harrison BJ; Melbourne Neuropsychiatry Centre, Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia., Ho TC; Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; Department of Psychology, University of California, Los Angeles, CA, USA., Jahanshad N; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, 90274, USA., Jamieson AJ; Melbourne Neuropsychiatry Centre, Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia., Karuk A; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Catalonia, Spain., Kircher T; Department of Psychiatry and Psychotherapy, University of Marburg, Rudolf Bultmann Str. 8, 35039, Marburg, Germany., Klimes-Dougan B; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Koopowitz SM; Department of Psychiatry & Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Lancaster T; Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, UK.; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Leenings R; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Li M; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Linden DEJ; Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, UK.; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.; School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, 6229 ER, the Netherlands., MacMaster FP; Departments of Psychiatry and Pediatrics, University of Calgary, Calgary, AB, Canada., Mehler DMA; Institute for Translational Psychiatry, University of Münster, Münster, Germany.; Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, UK.; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Aachen, Germany., Meinert S; Institute for Translational Psychiatry, University of Münster, Münster, Germany.; Institute for Translational Neuroscience, University of Münster, Münster, Germany., Melloni E; Division of Neuroscience, IRCCS Scientific Institute Ospedale San Raffaele, Milano, Italy., Mueller BA; Department of Psychiatry and Behavioral Science, University of Minnesota Medical School, Minneapolis, MN, USA., Mwangi B; Center Of Excellence on Mood Disorders, Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA., Nenadić I; Department of Psychiatry and Psychotherapy, University of Marburg, Rudolf Bultmann Str. 8, 35039, Marburg, Germany., Ojha A; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA., Okamoto Y; Department of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan., Oudega ML; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; GGZ inGeest Mental Health Care, Amsterdam, the Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Poletti S; Division of Neuroscience, IRCCS Scientific Institute Ospedale San Raffaele, Milano, Italy., Pomarol-Clotet E; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Catalonia, Spain., Portella MJ; Sant Pau Mental Health Research Group, Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain.; CIBERSAM, Madrid, Spain., Radua J; Imaging of Mood- and Anxiety-Related Disorders (IMARD) Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Rodríguez-Cano E; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Catalonia, Spain., Sacchet MD; Meditation Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Salvador R; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Catalonia, Spain., Schrantee A; Amsterdam University Medical Centers, location AMC, Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands., Sim K; West Region, Institute of Mental Health, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Soares JC; Center Of Excellence on Mood Disorders, Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA., Solanes A; Imaging of Mood- and Anxiety-Related Disorders (IMARD) Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Stein DJ; Department of Psychiatry & Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Stein F; Department of Psychiatry and Psychotherapy, University of Marburg, Rudolf Bultmann Str. 8, 35039, Marburg, Germany., Stolicyn A; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Scotland, UK., Thomopoulos SI; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, 90274, USA., Toenders YJ; Centre for Youth Mental Health, the University of Melbourne, Parkville, VIC, Australia.; Orygen, Parkville, VIC, Australia.; Developmental and Educational Psychology, Leiden University, Leiden, the Netherlands.; Erasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, the Netherlands., Uyar-Demir A; SoCAT Lab, Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey., Vieta E; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain., Vives-Gilabert Y; Intelligent Data Analysis Laboratory (IDAL), Department of Electronic Engineering, Universitat de València, Valencia, Spain., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Walter M; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Whalley HC; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Scotland, UK., Whittle S; Melbourne Neuropsychiatry Centre, Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia., Winter N; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Wittfeld K; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Wright MJ; Queensland Brain Institute, the University of Queensland, Brisbane, QLD, Australia.; Centre for Advanced Imaging, the University of Queensland, Brisbane, QLD, Australia., Wu MJ; Center Of Excellence on Mood Disorders, Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA., Yang TT; Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Zarate C; Section on the Neurobiology and Treatment of Mood Disorders, National Institute of Mental Health, Bethesda, MD, USA., Veltman DJ; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Schmaal L; Centre for Youth Mental Health, the University of Melbourne, Parkville, VIC, Australia.; Orygen, Parkville, VIC, Australia., Thompson PM; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, 90274, USA. |
| Corporate Authors: | ENIGMA Major Depressive Disorder working group |
| Source: | Molecular psychiatry [Mol Psychiatry] 2026 Mar; Vol. 31 (3), pp. 1517-1529. Date of Electronic Publication: 2025 Oct 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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