Design and development of N-Heterocyclic protease inhibitors for flaviviral infections: a synthetic and SAR-based review.

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Title: Design and development of N-Heterocyclic protease inhibitors for flaviviral infections: a synthetic and SAR-based review.
Authors: Nath R; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.; Department of Pharmaceutical Technology, JIS University, Agarpara Campus, Kolkata, West Bengal, 700109, India., Akhtar MJ; Department of Pharmaceutical Chemistry, National University of Science and Technology, PC-130, Azaiba, Boucher, PO-620, Muscat, Sultanate of Oman., Pradhan SS; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India., Mal SK; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India., Panda S; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India., Ashique S; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India., Maity A; Department of Pharmaceutical Technology, JIS University, Agarpara Campus, Kolkata, West Bengal, 700109, India., Bandyopadhyay K; Department of Pharmacology, JSS College of Pharmacy, Bangalore-Mysore Road, Bannimantap, Mysuru, Karnataka, 570015, India., Paul S; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India., Khan SA; Department of Pharmaceutical Chemistry, National University of Science and Technology, PC-130, Azaiba, Boucher, PO-620, Muscat, Sultanate of Oman., Nehra B; Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India., Debnath B; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India. biplab.d86@gmail.com., Al-Salem FM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, 62529, Abha, Saudi Arabia., Yasmin S; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, 62529, Abha, Saudi Arabia., Ansari MY; Ibne Seena Pharmacy College, AMES Group of Institutions, Shahabad, Hardoi, 241124, India. director.260@aktu.ac.in.
Source: Molecular diversity [Mol Divers] 2026 Jun; Vol. 30 (3), pp. 3259-3289. Date of Electronic Publication: 2025 Oct 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design and development of N-Heterocyclic protease inhibitors for flaviviral infections: a synthetic and SAR-based review.
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  Data: <searchLink fieldCode="AU" term="%22Nath+R%22">Nath R</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.; Department of Pharmaceutical Technology, JIS University, Agarpara Campus, Kolkata, West Bengal, 700109, India.<br /><searchLink fieldCode="AU" term="%22Akhtar+MJ%22">Akhtar MJ</searchLink>; Department of Pharmaceutical Chemistry, National University of Science and Technology, PC-130, Azaiba, Boucher, PO-620, Muscat, Sultanate of Oman.<br /><searchLink fieldCode="AU" term="%22Pradhan+SS%22">Pradhan SS</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.<br /><searchLink fieldCode="AU" term="%22Mal+SK%22">Mal SK</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.<br /><searchLink fieldCode="AU" term="%22Panda+S%22">Panda S</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.<br /><searchLink fieldCode="AU" term="%22Ashique+S%22">Ashique S</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.<br /><searchLink fieldCode="AU" term="%22Maity+A%22">Maity A</searchLink>; Department of Pharmaceutical Technology, JIS University, Agarpara Campus, Kolkata, West Bengal, 700109, India.<br /><searchLink fieldCode="AU" term="%22Bandyopadhyay+K%22">Bandyopadhyay K</searchLink>; Department of Pharmacology, JSS College of Pharmacy, Bangalore-Mysore Road, Bannimantap, Mysuru, Karnataka, 570015, India.<br /><searchLink fieldCode="AU" term="%22Paul+S%22">Paul S</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India.<br /><searchLink fieldCode="AU" term="%22Khan+SA%22">Khan SA</searchLink>; Department of Pharmaceutical Chemistry, National University of Science and Technology, PC-130, Azaiba, Boucher, PO-620, Muscat, Sultanate of Oman.<br /><searchLink fieldCode="AU" term="%22Nehra+B%22">Nehra B</searchLink>; Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.<br /><searchLink fieldCode="AU" term="%22Debnath+B%22">Debnath B</searchLink>; Department of Pharmaceutical Technology, Bharat Technology, Uluberia, Howrah, West Bengal, 711316, India. biplab.d86@gmail.com.<br /><searchLink fieldCode="AU" term="%22Al-Salem+FM%22">Al-Salem FM</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, 62529, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Yasmin+S%22">Yasmin S</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, 62529, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ansari+MY%22">Ansari MY</searchLink>; Ibne Seena Pharmacy College, AMES Group of Institutions, Shahabad, Hardoi, 241124, India. director.260@aktu.ac.in.
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