Novel anticancer effect of substituted imidazole derivatives against urothelial carcinoma: integrating In vitro screening and molecular docking for target kinases.
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| Title: | Novel anticancer effect of substituted imidazole derivatives against urothelial carcinoma: integrating In vitro screening and molecular docking for target kinases. |
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| Authors: | Aboulhoda BE; Department of Anatomy and Embryology, Faculty of Medicine, Cairo University, Cairo, Egypt. basma.emad@kasralainy.edu.eg., Omar AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Elfarrash S; Department of Medical Physiology, Faculty of Medicine, Mansoura University, 35516, Mansoura, Egypt.; Medical Experimental Research Center (MERC), Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt., Alghamdi MA; Central Labs, King Khalid University, P.O. Box 960, AlQura'a, Abha, Saudi Arabia.; Department of Anatomy, College of Medicine, King Khalid University, Abha, 62529, Saudi Arabia.; Genomics and Personalized Medicine Unit, The Center for Medical and Health Research, King Khalid University, Abha, 62529, Saudi Arabia., Emam AA; Medical Experimental Research Center (MERC), Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt., El-Gamal R; Medical Experimental Research Center (MERC), Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.; Department of Medical Biochemistry, Horus University- Egypt (HUE), Cairo, Egypt., Abo-Elhoda SE; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt., Zayed MF; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, 11884, Egypt. |
| Source: | BMC cancer [BMC Cancer] 2025 Oct 06; Vol. 25 (1), pp. 1524. Date of Electronic Publication: 2025 Oct 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1471-2407 |
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| DOI: | 10.1186/s12885-025-15012-z |
