Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease.

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Title: Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease.
Authors: Kim D; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. daeeun.kim@unc.edu.; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. daeeun.kim@unc.edu., Highland HM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Brownsville, TX, USA., Smit RAJ; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Hysong MR; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Buchanan VL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Brownsville, TX, USA., Young KL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Brownsville, TX, USA., Zhao C; Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA., Spracklen CN; Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Guo B; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Darst BF; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Cai Y; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Wang Z; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lundin J; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD, USA., Manson JE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Marouli E; Barts and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK., Lange L; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Lange E; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Gignoux CR; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Haiman CA; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Rich SS; Center for Public Health Genomics, University of Virginia Charlottesville, Charlottesville, VA, USA., Buyske S; Department of Genetics, Rutgers University, Piscataway, NJ, USA., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Avery CL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gordon-Larsen P; Department of Nutrition, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Raffield LM; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Kari.E.North@uth.tmc.edu.; Department of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Brownsville, TX, USA. Kari.E.North@uth.tmc.edu.; Border Health Research Center, UTHealth Houston School of Public Health, 780 Ringgold Road, Brownsville, TX, 78520‑4979, USA. Kari.E.North@uth.tmc.edu.; Department of Internal Medicine, McGovern Medical School, UTHealth Houston School of Public Health, 780 Ringgold Road, Brownsville, TX, 78520‑4979, USA. Kari.E.North@uth.tmc.edu.
Source: Genome medicine [Genome Med] 2025 Oct 06; Vol. 17 (1), pp. 113. Date of Electronic Publication: 2025 Oct 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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