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The secreted metabolite sensor CtBP2 links metabolism to healthy lifespan.

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Title: The secreted metabolite sensor CtBP2 links metabolism to healthy lifespan.
Authors: Sekiya M; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan. msekiya@md.tsukuba.ac.jp., Kainoh K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Chen W; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Yamazaki D; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Tsuyuzaki T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Kobari Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Nakata A; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Saito K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Aono-Soma N; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Majid A; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Ohno H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Miyamoto T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Matsuzaka T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan., Nakajima R; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Matsuda T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Murayama Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Sugano Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Osaki Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Iwasaki H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Shimano H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Source: Nature aging [Nat Aging] 2025 Nov; Vol. 5 (11), pp. 2197-2214. Date of Electronic Publication: 2025 Oct 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE
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  Data: The secreted metabolite sensor CtBP2 links metabolism to healthy lifespan.
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  Data: <searchLink fieldCode="AU" term="%22Sekiya+M%22">Sekiya M</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan. msekiya@md.tsukuba.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kainoh+K%22">Kainoh K</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Yamazaki+D%22">Yamazaki D</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuyuzaki+T%22">Tsuyuzaki T</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kobari+Y%22">Kobari Y</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Nakata+A%22">Nakata A</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+K%22">Saito K</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Aono-Soma+N%22">Aono-Soma N</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Majid+A%22">Majid A</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Ohno+H%22">Ohno H</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Miyamoto+T%22">Miyamoto T</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuzaka+T%22">Matsuzaka T</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+R%22">Nakajima R</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuda+T%22">Matsuda T</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Murayama+Y%22">Murayama Y</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Sugano+Y%22">Sugano Y</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Osaki+Y%22">Osaki Y</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Iwasaki+H%22">Iwasaki H</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Shimano+H%22">Shimano H</searchLink>; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101773306%22">Nature aging</searchLink> [Nat Aging] 2025 Nov; Vol. 5 (11), pp. 2197-2214. <i>Date of Electronic Publication: </i>2025 Oct 08.
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