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A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.

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Title: A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
Authors: Shen X; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK., Barbu M; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK., Caramaschi D; Faculty of Health and Life Sciences, Department of Psychology, University of Exeter, Exeter, UK., Arathimos R; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Czamara D; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany., David FS; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany., Dearman A; Institute for Social and Economic Research, University of Essex, Colchester, UK., Dilkes E; Institute for Social and Economic Research, University of Essex, Colchester, UK., Herrera-Rivero M; Department of Genetic Epidemiology, Institute of Human Genetics, University of Münster, Münster, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Huider F; Biological Psychology, Amsterdam Public Health Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Kühn L; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Lu KC; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan., Palviainen T; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Schowe AM; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; Ludwig-Maximilians-Universität, Graduate School of Systemic Neuroscience, Munich, Germany., Shireby G; University of Exeter Medical School, University of Exeter, Exeter, UK.; Institute of Education, University College London, London, UK., Weihs A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Greifswald, Germany., Wong CCY; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Davyson E; School of Informatics, University of Edinburgh, Edinburgh, UK., Casey H; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK., Adams MJ; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK., Allgaier AK; Department of Human Sciences, University of the Bundeswehr Munich, Munich, Germany., Barber M; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK., Burrage J; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Caspi A; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Departments of Psychology and Neuroscience, Psychiatry and Behavioral Sciences, and Institute for Genome Sciences and Policy, Duke University, Durham, NC USA., Costeira R; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Dunn EC; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA USA.; Department of Psychiatry, Harvard Medical School, Boston, MA USA., Feldmann L; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Freisleder FJ; kbo-Heckscher-Klinikum gGmbH, Munich, Germany., Gadd DA; Institute of Genetics and Cancer, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Greimel E; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany., Hannon E; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Harris SE; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Howard DM; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Iurato S; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; Roche Diagnostics GmbH, Munich, Germany., Korhonen T; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Lu TP; Department of Public Health and Institute of Health Data Analytics and Statistics, National Taiwan University, Taipei, Taiwan., Martin NG; Queensland Institute of Medical Research Berghofer, Brisbane, Queensland Australia., Martins J; Decision Intelligence, Knorr-Bremse Services GmbH, Munich, Germany., McDermott E; Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland., Meinert S; Institute for Translational Psychiatry, University of Münster, Münster, Germany.; Institute for Translational Neuroscience, University of Münster, Münster, Germany., Navarro P; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.; The Roslin Institute, University of Edinburgh, Edinburgh, UK., Ollikainen M; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Pehl V; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany., Piechaczek C; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany., Scherff AD; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany., Stein F; Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg, Marburg, Germany., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), Partner Site Mannheim-Heidelberg-Ulm, Mannheim, Germany., Teumer A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), Greifswald, Germany., Völzke H; German Centre for Cardiovascular Research (DZHK), Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., van Dongen J; Biological Psychology, Amsterdam Public Health Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Walker RM; Faculty of Health and Life Sciences, Department of Psychology, University of Exeter, Exeter, UK., Yusupov N; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany., Arseneault L; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Binder E; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany., Boomsma DI; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Cox SR; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Dannlowski U; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Evans KL; Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Fisher HL; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; ESRC Centre for Society and Mental Health, King's College London, London, UK., Forstner AJ; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Greifswald, Germany., Kaprio J; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Kircher T; Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg, Marburg, Germany., Kopf-Beck J; Clinical Department, Max Planck Institute of Psychiatry, Munich, Germany.; Department of Psychology, LMU Munich, Munich, Germany., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, UK., Kuo PH; Department of Public Health & Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Li QS; Neuroscience, Janssen Research and Development, Titusville, NJ USA., Moffitt TE; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Departments of Psychology and Neuroscience, Psychiatry and Behavioral Sciences, and Institute for Genome Sciences and Policy, Duke University, Durham, NC USA., Mulcahy H; Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland.; School of Medicine, University College Dublin, Dublin, Ireland., Murphy TM; School of Biological, Health and Sports Sciences, Technological University Dublin, Dublin, Ireland., Schulte-Körne G; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany., Mill J; University of Exeter Medical School, University of Exeter, Exeter, UK.; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Lewis CM; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Wray NR; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland Australia.; Department of Psychiatry, University of Oxford, Oxford, UK., McIntosh AM; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.
Corporate Authors: PGC MDD Working Group
Source: Nature. Mental health [Nat Ment Health] 2025; Vol. 3 (10), pp. 1152-1167. Date of Electronic Publication: 2025 Sep 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918486688806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-6076 (Electronic) Linking ISSN: 27316076 NLM ISO Abbreviation: Nat Ment Health Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Label: Title
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  Data: A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Shen+X%22">Shen X</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Barbu+M%22">Barbu M</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Caramaschi+D%22">Caramaschi D</searchLink>; Faculty of Health and Life Sciences, Department of Psychology, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Arathimos+R%22">Arathimos R</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Czamara+D%22">Czamara D</searchLink>; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22David+FS%22">David FS</searchLink>; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Dearman+A%22">Dearman A</searchLink>; Institute for Social and Economic Research, University of Essex, Colchester, UK.<br /><searchLink fieldCode="AU" term="%22Dilkes+E%22">Dilkes E</searchLink>; Institute for Social and Economic Research, University of Essex, Colchester, UK.<br /><searchLink fieldCode="AU" term="%22Herrera-Rivero+M%22">Herrera-Rivero M</searchLink>; Department of Genetic Epidemiology, Institute of Human Genetics, University of Münster, Münster, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Huider+F%22">Huider F</searchLink>; Biological Psychology, Amsterdam Public Health Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kühn+L%22">Kühn L</searchLink>; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Lu+KC%22">Lu KC</searchLink>; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Palviainen+T%22">Palviainen T</searchLink>; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Schowe+AM%22">Schowe AM</searchLink>; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; Ludwig-Maximilians-Universität, Graduate School of Systemic Neuroscience, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Shireby+G%22">Shireby G</searchLink>; University of Exeter Medical School, University of Exeter, Exeter, UK.; Institute of Education, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Weihs+A%22">Weihs A</searchLink>; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Wong+CCY%22">Wong CCY</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Davyson+E%22">Davyson E</searchLink>; School of Informatics, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Casey+H%22">Casey H</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Adams+MJ%22">Adams MJ</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Allgaier+AK%22">Allgaier AK</searchLink>; Department of Human Sciences, University of the Bundeswehr Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Barber+M%22">Barber M</searchLink>; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Burrage+J%22">Burrage J</searchLink>; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Caspi+A%22">Caspi A</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Departments of Psychology and Neuroscience, Psychiatry and Behavioral Sciences, and Institute for Genome Sciences and Policy, Duke University, Durham, NC USA.<br /><searchLink fieldCode="AU" term="%22Costeira+R%22">Costeira R</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Dunn+EC%22">Dunn EC</searchLink>; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA USA.; Department of Psychiatry, Harvard Medical School, Boston, MA USA.<br /><searchLink fieldCode="AU" term="%22Feldmann+L%22">Feldmann L</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Frank+J%22">Frank J</searchLink>; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Freisleder+FJ%22">Freisleder FJ</searchLink>; kbo-Heckscher-Klinikum gGmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gadd+DA%22">Gadd DA</searchLink>; Institute of Genetics and Cancer, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Greimel+E%22">Greimel E</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hannon+E%22">Hannon E</searchLink>; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Harris+SE%22">Harris SE</searchLink>; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Homuth+G%22">Homuth G</searchLink>; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Howard+DM%22">Howard DM</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Iurato+S%22">Iurato S</searchLink>; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; Roche Diagnostics GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Korhonen+T%22">Korhonen T</searchLink>; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lu+TP%22">Lu TP</searchLink>; Department of Public Health and Institute of Health Data Analytics and Statistics, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; Queensland Institute of Medical Research Berghofer, Brisbane, Queensland Australia.<br /><searchLink fieldCode="AU" term="%22Martins+J%22">Martins J</searchLink>; Decision Intelligence, Knorr-Bremse Services GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22McDermott+E%22">McDermott E</searchLink>; Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Meinert+S%22">Meinert S</searchLink>; Institute for Translational Psychiatry, University of Münster, Münster, Germany.; Institute for Translational Neuroscience, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Navarro+P%22">Navarro P</searchLink>; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.; The Roslin Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ollikainen+M%22">Ollikainen M</searchLink>; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Pehl+V%22">Pehl V</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Piechaczek+C%22">Piechaczek C</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Scherff+AD%22">Scherff AD</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Stein+F%22">Stein F</searchLink>; Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Streit+F%22">Streit F</searchLink>; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), Partner Site Mannheim-Heidelberg-Ulm, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Teumer+A%22">Teumer A</searchLink>; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Völzke+H%22">Völzke H</searchLink>; German Centre for Cardiovascular Research (DZHK), Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22van+Dongen+J%22">van Dongen J</searchLink>; Biological Psychology, Amsterdam Public Health Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Walker+RM%22">Walker RM</searchLink>; Faculty of Health and Life Sciences, Department of Psychology, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Yusupov+N%22">Yusupov N</searchLink>; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Arseneault+L%22">Arseneault L</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bell+JT%22">Bell JT</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Berger+K%22">Berger K</searchLink>; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Binder+E%22">Binder E</searchLink>; Department Genes and Environment, Max-Planck-Institute of Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Boomsma+DI%22">Boomsma DI</searchLink>; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cox+SR%22">Cox SR</searchLink>; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Dannlowski+U%22">Dannlowski U</searchLink>; Institute for Translational Psychiatry, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Evans+KL%22">Evans KL</searchLink>; Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Fisher+HL%22">Fisher HL</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; ESRC Centre for Society and Mental Health, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Forstner+AJ%22">Forstner AJ</searchLink>; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Grabe+HJ%22">Grabe HJ</searchLink>; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Kaprio+J%22">Kaprio J</searchLink>; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kircher+T%22">Kircher T</searchLink>; Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kopf-Beck+J%22">Kopf-Beck J</searchLink>; Clinical Department, Max Planck Institute of Psychiatry, Munich, Germany.; Department of Psychology, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kumari+M%22">Kumari M</searchLink>; Institute for Social and Economic Research, University of Essex, Colchester, UK.<br /><searchLink fieldCode="AU" term="%22Kuo+PH%22">Kuo PH</searchLink>; Department of Public Health & Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+QS%22">Li QS</searchLink>; Neuroscience, Janssen Research and Development, Titusville, NJ USA.<br /><searchLink fieldCode="AU" term="%22Moffitt+TE%22">Moffitt TE</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Departments of Psychology and Neuroscience, Psychiatry and Behavioral Sciences, and Institute for Genome Sciences and Policy, Duke University, Durham, NC USA.<br /><searchLink fieldCode="AU" term="%22Mulcahy+H%22">Mulcahy H</searchLink>; Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland.; School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Murphy+TM%22">Murphy TM</searchLink>; School of Biological, Health and Sports Sciences, Technological University Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Schulte-Körne+G%22">Schulte-Körne G</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich-Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mill+J%22">Mill J</searchLink>; University of Exeter Medical School, University of Exeter, Exeter, UK.; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Lewis+CM%22">Lewis CM</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wray+NR%22">Wray NR</searchLink>; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland Australia.; Department of Psychiatry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McIntosh+AM%22">McIntosh AM</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.
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  Data: <searchLink fieldCode="JN" term="%229918486688806676%22">Nature. Mental health</searchLink> [Nat Ment Health] 2025; Vol. 3 (10), pp. 1152-1167. <i>Date of Electronic Publication: </i>2025 Sep 16.
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  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918486688806676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2731-6076 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227316076%22">27316076 </searchLink><i>NLM ISO Abbreviation: </i>Nat Ment Health <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41069367
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      – Type: doi
        Value: 10.1038/s44220-025-00486-4
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      – Code: eng
        Text: English
    PhysicalDescription:
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      – TitleFull: A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
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              Text: 2025
              Type: published
              Y: 2025
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            – TitleFull: Nature. Mental health
              Type: main
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