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Proposal of a novel model for identifying complete response and nonoperative management in dMMR colon cancer following neoadjuvant immunotherapy: a retrospective cohort study.

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Title: Proposal of a novel model for identifying complete response and nonoperative management in dMMR colon cancer following neoadjuvant immunotherapy: a retrospective cohort study.
Authors: Liao LE; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Feng LL; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China., Chen BY; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China., Xiao BY; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Yu JH; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Cai ZR; Department of Colorectal Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Jiang W; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Luo GY; Department of Endoscopy, Sun Yat-sen University Cancer Center, Guangzhou, China., Tang JH; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Hou ZL; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Zhang CZ; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Mei WJ; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Yang WJ; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Pan ZZ; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Han K; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China., Wu XJ; Department of Colorectal Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Ding PR; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.
Source: International journal of surgery (London, England) [Int J Surg] 2026 Feb 01; Vol. 112 (2), pp. 3808-3817. Date of Electronic Publication: 2025 Oct 11.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Liao+LE%22">Liao LE</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Feng+LL%22">Feng LL</searchLink>; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+BY%22">Chen BY</searchLink>; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xiao+BY%22">Xiao BY</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+JH%22">Yu JH</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cai+ZR%22">Cai ZR</searchLink>; Department of Colorectal Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+W%22">Jiang W</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Luo+GY%22">Luo GY</searchLink>; Department of Endoscopy, Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tang+JH%22">Tang JH</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hou+ZL%22">Hou ZL</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+CZ%22">Zhang CZ</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Mei+WJ%22">Mei WJ</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+WJ%22">Yang WJ</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Pan+ZZ%22">Pan ZZ</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Han+K%22">Han K</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+XJ%22">Wu XJ</searchLink>; Department of Colorectal Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ding+PR%22">Ding PR</searchLink>; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101228232%22">International journal of surgery (London, England)</searchLink> [Int J Surg] 2026 Feb 01; Vol. 112 (2), pp. 3808-3817. <i>Date of Electronic Publication: </i>2025 Oct 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101228232 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1743-9159 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217439159%22">17439159 </searchLink><i>NLM ISO Abbreviation: </i>Int J Surg <i>Subsets: </i>MEDLINE
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        Value: 10.1097/JS9.0000000000003602
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