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Quantification of plasma APOE4 with a novel automated Lumipulse immunoassay enables the identification of homozygous and heterozygous APOE ε4 carrier status.

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Title: Quantification of plasma APOE4 with a novel automated Lumipulse immunoassay enables the identification of homozygous and heterozygous APOE ε4 carrier status.
Authors: Musso G; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy. Electronic address: giulia.musso@unipd.it., Cosma C; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy., Moz S; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy., Gabelli C; Regional Brain Aging Center, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy., Navaglia F; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy., Codemo A; Regional Brain Aging Center, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy., Zambon CF; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy., Cagnin A; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; Padova Neuroscience Center (PNC), University of Padova, via Giuseppe Orus, 2/b, 35131 Padova, Italy., Antonini A; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; IRCCS San Camillo, Venezia, Italy., Corbetta M; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; Padova Neuroscience Center (PNC), University of Padova, via Giuseppe Orus, 2/b, 35131 Padova, Italy., Montagnana M; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.
Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2026 Jan 15; Vol. 579, pp. 120659. Date of Electronic Publication: 2025 Oct 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3492 (Electronic) Linking ISSN: 00098981 NLM ISO Abbreviation: Clin Chim Acta Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Quantification of plasma APOE4 with a novel automated Lumipulse immunoassay enables the identification of homozygous and heterozygous APOE ε4 carrier status.
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  Data: <searchLink fieldCode="AU" term="%22Musso+G%22">Musso G</searchLink>; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy. Electronic address: giulia.musso@unipd.it.<br /><searchLink fieldCode="AU" term="%22Cosma+C%22">Cosma C</searchLink>; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Moz+S%22">Moz S</searchLink>; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Gabelli+C%22">Gabelli C</searchLink>; Regional Brain Aging Center, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Navaglia+F%22">Navaglia F</searchLink>; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Codemo+A%22">Codemo A</searchLink>; Regional Brain Aging Center, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Zambon+CF%22">Zambon CF</searchLink>; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Cagnin+A%22">Cagnin A</searchLink>; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; Padova Neuroscience Center (PNC), University of Padova, via Giuseppe Orus, 2/b, 35131 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Antonini+A%22">Antonini A</searchLink>; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; IRCCS San Camillo, Venezia, Italy.<br /><searchLink fieldCode="AU" term="%22Corbetta+M%22">Corbetta M</searchLink>; Department of Neuroscience (DNS), University of Padova, via Giustiniani, 5, 35128 Padova, Italy; Padova Neuroscience Center (PNC), University of Padova, via Giuseppe Orus, 2/b, 35131 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Montagnana+M%22">Montagnana M</searchLink>; Department of Medicine - DIMED, University of Padova, via Giustiniani, 2, 35128 Padova, Italy; Laboratory Medicine, University-Hospital of Padova, via Giustiniani, 2, 35128 Padova, Italy.
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  Data: <searchLink fieldCode="JN" term="%221302422%22">Clinica chimica acta; international journal of clinical chemistry</searchLink> [Clin Chim Acta] 2026 Jan 15; Vol. 579, pp. 120659. <i>Date of Electronic Publication: </i>2025 Oct 12.
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              Text: 2026 Jan 15
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