Long-term metabolic and safety profiles of tenofovir alafenamide and tenofovir disoproxil fumarate in ART-naive people living with HIV: a multicenter retrospective study using a mixed-effects model.

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Title: Long-term metabolic and safety profiles of tenofovir alafenamide and tenofovir disoproxil fumarate in ART-naive people living with HIV: a multicenter retrospective study using a mixed-effects model.
Authors: Karabay O; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye. okarabay@sakarya.edu.tr.; Medical Research and Development, ARGE. Technology Transfer Office of Sakarya University, Sakarya, Türkiye. okarabay@sakarya.edu.tr., Vatan A; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye., Ucar A; Department of Public Health, Faculty of Medicine, Sakarya University, Sakarya, Türkiye., Yilmaz I; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye., Balta NC; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye., Kanturk A; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, Türkiye., Dumlu R; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Medipol University, Istanbul, Türkiye., Cag Y; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye., Caskurlu H; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye., Şik MT; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye., Otman ZA; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye., Balci U; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye., Senbayrak S; Department of Infectious Diseases and Clinical Microbiology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye., Akhan S; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli, Türkiye., Deniz MT; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli, Türkiye., Yekenkurul D; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye., Ince N; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye., Tunca B; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye., Cakirca TD; Department of Infectious Diseases and Clinical Microbiology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye., Bastug A; Department of Infectious Diseases and Clinical Microbiology, University of Health Science, Ankara Bilkent City Hospital, Ankara, Türkiye., Erkorkmaz U; Department of Biostatistics, Faculty of Medicine, Sakarya University, Sakarya, Türkiye., Guclu E; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.
Source: BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2025 Oct 14; Vol. 26 (1), pp. 164. Date of Electronic Publication: 2025 Oct 14.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590449 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-6511 (Electronic) Linking ISSN: 20506511 NLM ISO Abbreviation: BMC Pharmacol Toxicol Subsets: MEDLINE
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  Data: Long-term metabolic and safety profiles of tenofovir alafenamide and tenofovir disoproxil fumarate in ART-naive people living with HIV: a multicenter retrospective study using a mixed-effects model.
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  Data: <searchLink fieldCode="AU" term="%22Karabay+O%22">Karabay O</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye. okarabay@sakarya.edu.tr.; Medical Research and Development, ARGE. Technology Transfer Office of Sakarya University, Sakarya, Türkiye. okarabay@sakarya.edu.tr.<br /><searchLink fieldCode="AU" term="%22Vatan+A%22">Vatan A</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ucar+A%22">Ucar A</searchLink>; Department of Public Health, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Yilmaz+I%22">Yilmaz I</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Balta+NC%22">Balta NC</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Kanturk+A%22">Kanturk A</searchLink>; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Dumlu+R%22">Dumlu R</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Medipol University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Cag+Y%22">Cag Y</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Caskurlu+H%22">Caskurlu H</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Şik+MT%22">Şik MT</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Otman+ZA%22">Otman ZA</searchLink>; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Balci+U%22">Balci U</searchLink>; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Senbayrak+S%22">Senbayrak S</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Akhan+S%22">Akhan S</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli, Türkiye.<br /><searchLink fieldCode="AU" term="%22Deniz+MT%22">Deniz MT</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli, Türkiye.<br /><searchLink fieldCode="AU" term="%22Yekenkurul+D%22">Yekenkurul D</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ince+N%22">Ince N</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye.<br /><searchLink fieldCode="AU" term="%22Tunca+B%22">Tunca B</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Düzce University, Düzce, Türkiye.<br /><searchLink fieldCode="AU" term="%22Cakirca+TD%22">Cakirca TD</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.<br /><searchLink fieldCode="AU" term="%22Bastug+A%22">Bastug A</searchLink>; Department of Infectious Diseases and Clinical Microbiology, University of Health Science, Ankara Bilkent City Hospital, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Erkorkmaz+U%22">Erkorkmaz U</searchLink>; Department of Biostatistics, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.<br /><searchLink fieldCode="AU" term="%22Guclu+E%22">Guclu E</searchLink>; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.
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  Data: <searchLink fieldCode="JN" term="%22101590449%22">BMC pharmacology & toxicology</searchLink> [BMC Pharmacol Toxicol] 2025 Oct 14; Vol. 26 (1), pp. 164. <i>Date of Electronic Publication: </i>2025 Oct 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101590449 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-6511 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220506511%22">20506511 </searchLink><i>NLM ISO Abbreviation: </i>BMC Pharmacol Toxicol <i>Subsets: </i>MEDLINE
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