General Synthesis and Properties of Bridged, Fused, and Spirocyclic Azacycles via Intramolecular C-H Bond Amination.
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| Title: | General Synthesis and Properties of Bridged, Fused, and Spirocyclic Azacycles via Intramolecular C-H Bond Amination. |
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| Authors: | Lux MC; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Jurczyk J; Department of Chemistry, University of California, Berkeley, California 94720, United States., Adpressa D; Analytical Research & Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lam YH; Computational and Structural Chemistry, Merck & Co., Inc., 90 E. Scott Avenue, Rahway, New Jersey 07065, United States., Ma C; WuXi Apptec Co., Ltd. 168 Nanhai Road, Tianjin Economic-Technological Development Area (TDEA), Tianjin 330457 China., Song ZJ; External Discovery Process Chemistry, Process Research & Development, Merck & Co., Inc., 126 E. Lincoln Avenue, Rahway, New Jersey 07065, United States., Sciammetta N; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Sarpong R; Department of Chemistry, University of California, Berkeley, California 94720, United States., Yeung CS; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Sep 25; Vol. 16 (10), pp. 2049-2056. Date of Electronic Publication: 2025 Sep 25 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41089491 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: General Synthesis and Properties of Bridged, Fused, and Spirocyclic Azacycles via Intramolecular C-H Bond Amination. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lux+MC%22">Lux MC</searchLink>; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.<br /><searchLink fieldCode="AU" term="%22Jurczyk+J%22">Jurczyk J</searchLink>; Department of Chemistry, University of California, Berkeley, California 94720, United States.<br /><searchLink fieldCode="AU" term="%22Adpressa+D%22">Adpressa D</searchLink>; Analytical Research & Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.<br /><searchLink fieldCode="AU" term="%22Lam+YH%22">Lam YH</searchLink>; Computational and Structural Chemistry, Merck & Co., Inc., 90 E. Scott Avenue, Rahway, New Jersey 07065, United States.<br /><searchLink fieldCode="AU" term="%22Ma+C%22">Ma C</searchLink>; WuXi Apptec Co., Ltd. 168 Nanhai Road, Tianjin Economic-Technological Development Area (TDEA), Tianjin 330457 China.<br /><searchLink fieldCode="AU" term="%22Song+ZJ%22">Song ZJ</searchLink>; External Discovery Process Chemistry, Process Research & Development, Merck & Co., Inc., 126 E. Lincoln Avenue, Rahway, New Jersey 07065, United States.<br /><searchLink fieldCode="AU" term="%22Sciammetta+N%22">Sciammetta N</searchLink>; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.<br /><searchLink fieldCode="AU" term="%22Sarpong+R%22">Sarpong R</searchLink>; Department of Chemistry, University of California, Berkeley, California 94720, United States.<br /><searchLink fieldCode="AU" term="%22Yeung+CS%22">Yeung CS</searchLink>; Discovery Chemistry, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101521073%22">ACS medicinal chemistry letters</searchLink> [ACS Med Chem Lett] 2025 Sep 25; Vol. 16 (10), pp. 2049-2056. <i>Date of Electronic Publication: </i>2025 Sep 25 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101521073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1948-5875 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219485875%22">19485875 </searchLink><i>NLM ISO Abbreviation: </i>ACS Med Chem Lett <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41089491 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acsmedchemlett.5c00468 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2049 Titles: – TitleFull: General Synthesis and Properties of Bridged, Fused, and Spirocyclic Azacycles via Intramolecular C-H Bond Amination. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lux MC – PersonEntity: Name: NameFull: Jurczyk J – PersonEntity: Name: NameFull: Adpressa D – PersonEntity: Name: NameFull: Lam YH – PersonEntity: Name: NameFull: Ma C – PersonEntity: Name: NameFull: Song ZJ – PersonEntity: Name: NameFull: Sciammetta N – PersonEntity: Name: NameFull: Sarpong R – PersonEntity: Name: NameFull: Yeung CS IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 09 Text: 2025 Sep 25 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 1948-5875 Numbering: – Type: volume Value: 16 – Type: issue Value: 10 Titles: – TitleFull: ACS medicinal chemistry letters Type: main |
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