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A Real-World Phase IV Superiority Trial and Cost-Effectiveness Analysis of the Addition of Low-Dose Nivolumab to Triple Metronomic Chemotherapy Compared to the Paclitaxel Carboplatin Regimen in Recurrent or Metastatic Head and Neck Cancer Patients.

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Title: A Real-World Phase IV Superiority Trial and Cost-Effectiveness Analysis of the Addition of Low-Dose Nivolumab to Triple Metronomic Chemotherapy Compared to the Paclitaxel Carboplatin Regimen in Recurrent or Metastatic Head and Neck Cancer Patients.
Authors: Khadela A; Department of Pharmacology, LM. College of Pharmacy, Ahmedabad, Gujarat, India., Parikh R; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India., Vaghela J; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India., Chauhan Y; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India., Shah VB; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India., Kothari R; Oncowin Cancer Centre, Ahmedabad, Gujarat, India., Merja M; Sterling Hospital, Ahmedabad, Gujarat, India.
Source: Head & neck [Head Neck] 2026 Mar; Vol. 48 (3), pp. 765-773. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article; Clinical Trial, Phase IV; Comparative Study
Journal Info: Publisher: John Wiley And Sons Country of Publication: United States NLM ID: 8902541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0347 (Electronic) Linking ISSN: 10433074 NLM ISO Abbreviation: Head Neck Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Real-World Phase IV Superiority Trial and Cost-Effectiveness Analysis of the Addition of Low-Dose Nivolumab to Triple Metronomic Chemotherapy Compared to the Paclitaxel Carboplatin Regimen in Recurrent or Metastatic Head and Neck Cancer Patients.
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  Data: <searchLink fieldCode="AU" term="%22Khadela+A%22">Khadela A</searchLink>; Department of Pharmacology, LM. College of Pharmacy, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Parikh+R%22">Parikh R</searchLink>; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Vaghela+J%22">Vaghela J</searchLink>; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Chauhan+Y%22">Chauhan Y</searchLink>; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Shah+VB%22">Shah VB</searchLink>; Pharm. D Section, Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Kothari+R%22">Kothari R</searchLink>; Oncowin Cancer Centre, Ahmedabad, Gujarat, India.<br /><searchLink fieldCode="AU" term="%22Merja+M%22">Merja M</searchLink>; Sterling Hospital, Ahmedabad, Gujarat, India.
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  Data: <searchLink fieldCode="JN" term="%228902541%22">Head & neck</searchLink> [Head Neck] 2026 Mar; Vol. 48 (3), pp. 765-773. <i>Date of Electronic Publication: </i>2025 Oct 17.
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  Data: Journal Article; Clinical Trial, Phase IV; Comparative Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+And+Sons%22">John Wiley And Sons </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8902541 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-0347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210433074%22">10433074 </searchLink><i>NLM ISO Abbreviation: </i>Head Neck <i>Subsets: </i>MEDLINE
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        Value: 10.1002/hed.70077
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        Text: English
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      – TitleFull: A Real-World Phase IV Superiority Trial and Cost-Effectiveness Analysis of the Addition of Low-Dose Nivolumab to Triple Metronomic Chemotherapy Compared to the Paclitaxel Carboplatin Regimen in Recurrent or Metastatic Head and Neck Cancer Patients.
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              Text: 2026 Mar
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