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Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging.

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Title: Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging.
Authors: Jiang X; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Mahroo OA; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Khawaja AP; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK., Skowronska-Krawczyk D; Department of Ophthalmology, Center for Translational Vision Research, School of Medicine, UC Irvine, Irvine, CA, USA.; Department of Physiology and Biophysics, Center for Translational Vision Research, School of Medicine, UC Irvine, Irvine, CA, USA., Mackey DA; Centre for Ophthalmology and Visual Science (Incorporating the Lions Eye Institute), The University of Western Australia, Perth, Western Australia, Australia.; School of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia., Wiggs JL; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA., Hammond CJ; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Hysi PG; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; Sørlandet Sykehus Arendal, Arendal Hospital, Arendal, Norway.; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA., Bell CG; William Harvey Research Institute, Barts & The London Faculty of Medicine and Dentistry, Charterhouse Square, Queen Mary University of London, London, UK.; QMUL Centre for Epigenetics, Queen Mary University of London, London, UK.
Source: Epigenetics [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2566496. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mahroo+OA%22">Mahroo OA</searchLink>; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Khawaja+AP%22">Khawaja AP</searchLink>; Faculty of Brain Sciences, UCL Institute of Ophthalmology, London, UK.; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Skowronska-Krawczyk+D%22">Skowronska-Krawczyk D</searchLink>; Department of Ophthalmology, Center for Translational Vision Research, School of Medicine, UC Irvine, Irvine, CA, USA.; Department of Physiology and Biophysics, Center for Translational Vision Research, School of Medicine, UC Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mackey+DA%22">Mackey DA</searchLink>; Centre for Ophthalmology and Visual Science (Incorporating the Lions Eye Institute), The University of Western Australia, Perth, Western Australia, Australia.; School of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia.<br /><searchLink fieldCode="AU" term="%22Wiggs+JL%22">Wiggs JL</searchLink>; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hammond+CJ%22">Hammond CJ</searchLink>; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hysi+PG%22">Hysi PG</searchLink>; Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, London, UK.; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; Sørlandet Sykehus Arendal, Arendal Hospital, Arendal, Norway.; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bell+CG%22">Bell CG</searchLink>; William Harvey Research Institute, Barts & The London Faculty of Medicine and Dentistry, Charterhouse Square, Queen Mary University of London, London, UK.; QMUL Centre for Epigenetics, Queen Mary University of London, London, UK.
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  Data: <searchLink fieldCode="JN" term="%22101265293%22">Epigenetics</searchLink> [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2566496. <i>Date of Electronic Publication: </i>2025 Oct 17.
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              Text: 2025 Dec
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