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A novel protein cRERE encoded by a circular RNA directly targets ERK signaling to alleviate chemotherapy-induced neuropathic pain.

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Title: A novel protein cRERE encoded by a circular RNA directly targets ERK signaling to alleviate chemotherapy-induced neuropathic pain.
Authors: Zhang JB; Department of Pain Medicine, The Peking University Shenzhen Hospital, Shenzhen, 518036, P. R. China., Zhao ZB; Department of Pain Medicine, The Peking University Shenzhen Hospital, Shenzhen, 518036, P. R. China., Wu JY; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Institute of Neurological Diseases, Shenzhen Bay Laboratory, Gaoke Innovation Center, Shenzhen, 518132, P. R. China., Duan YJ; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Department of Anesthesiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, P.R. China., Zhou DQ; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China., Li Q; Department of Pain Management, People's Hospital of Longhua, Shenzhen, 518109, P.R. China., Ren XH; School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, P. R. China., Yang XH; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat- sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou, 510060, P. R. China., Zhao YT; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China., Zhao SQ; Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-sen University, Guangzhou, 510080, P. R. China., Chen MY; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China., Zhang XZ; Department of Hematology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510000, P. R. China., Xin WJ; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China. xinwj@mail.sysu.edu.cn.; School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, P. R. China. xinwj@mail.sysu.edu.cn., Guo GQ; Neuroscience Laboratory for Cognitive and Developmental Disorders, Department of Anatomy, Medical College of Jinan University, No. 601, Huangpu Avenue West, Guangzhou, 510630, P. R. China. tgqguo@jnu.edu.cn., Xie JD; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat- sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou, 510060, P. R. China. xiejd6@mail.sysu.edu.cn., Xu T; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China. xuting8@mail.sysu.edu.cn.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Oct 17; Vol. 23 (1), pp. 445. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel protein cRERE encoded by a circular RNA directly targets ERK signaling to alleviate chemotherapy-induced neuropathic pain.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+JB%22">Zhang JB</searchLink>; Department of Pain Medicine, The Peking University Shenzhen Hospital, Shenzhen, 518036, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhao+ZB%22">Zhao ZB</searchLink>; Department of Pain Medicine, The Peking University Shenzhen Hospital, Shenzhen, 518036, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wu+JY%22">Wu JY</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Institute of Neurological Diseases, Shenzhen Bay Laboratory, Gaoke Innovation Center, Shenzhen, 518132, P. R. China.<br /><searchLink fieldCode="AU" term="%22Duan+YJ%22">Duan YJ</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Department of Anesthesiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhou+DQ%22">Zhou DQ</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Pain Management, People's Hospital of Longhua, Shenzhen, 518109, P.R. China.<br /><searchLink fieldCode="AU" term="%22Ren+XH%22">Ren XH</searchLink>; School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, P. R. China.<br /><searchLink fieldCode="AU" term="%22Yang+XH%22">Yang XH</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat- sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou, 510060, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhao+YT%22">Zhao YT</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhao+SQ%22">Zhao SQ</searchLink>; Faculty of Forensic Medicine, Zhongshan Medical School, Sun Yat-sen University, Guangzhou, 510080, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+MY%22">Chen MY</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+XZ%22">Zhang XZ</searchLink>; Department of Hematology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510000, P. R. China.<br /><searchLink fieldCode="AU" term="%22Xin+WJ%22">Xin WJ</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China. xinwj@mail.sysu.edu.cn.; School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, P. R. China. xinwj@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Guo+GQ%22">Guo GQ</searchLink>; Neuroscience Laboratory for Cognitive and Developmental Disorders, Department of Anatomy, Medical College of Jinan University, No. 601, Huangpu Avenue West, Guangzhou, 510630, P. R. China. tgqguo@jnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xie+JD%22">Xie JD</searchLink>; Department of Anesthesiology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat- sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou, 510060, P. R. China. xiejd6@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xu+T%22">Xu T</searchLink>; Guangdong Province Key Laboratory of Brain Function and Disease, Department of Physiology and Pain Research Center, Zhongshan Medical School, Sun Yat-sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510080, P. R. China. xuting8@mail.sysu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170464 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-811X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221478811X%22">1478811X </searchLink><i>NLM ISO Abbreviation: </i>Cell Commun Signal <i>Subsets: </i>MEDLINE
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