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Bisphenol S chronic exposure impairs pancreatic function and induces obesity in male mice independently of high-fat diet intake.

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Title: Bisphenol S chronic exposure impairs pancreatic function and induces obesity in male mice independently of high-fat diet intake.
Authors: Alves APP; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Barreto-Reis E; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Gouvêa de Luca B; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Teaching and Research in Histology and Comparative Embryology, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Carvalho TS; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Sciences and Biotechnology Graduate Program, Fluminense Federal University, Niterofi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., de Andrade GP; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Sepúlveda-Fragoso V; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Alexandre-Santos B; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil., Proença Souza AB; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil., de Souza Vieira ALL; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil., Stockler-Pinto MB; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Frantz EDC; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil., Machado-Santos C; Laboratory of Teaching and Research in Histology and Comparative Embryology, Fluminense Federal University, Niteroi, RJ, Brazil., Pires de Carvalho D; Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro (UFRJ), Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Miranda-Alves L; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; Pharmacology and Medicinal Chemistry Graduate Program, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil; Morphological Sciences Graduate Program, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil., Magliano DC; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; Sciences and Biotechnology Graduate Program, Fluminense Federal University, Niterofi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil. Electronic address: dcmagliano@id.uff.br.
Source: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2026 Jan 01; Vol. 611, pp. 112689. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE
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  Data: Bisphenol S chronic exposure impairs pancreatic function and induces obesity in male mice independently of high-fat diet intake.
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  Data: <searchLink fieldCode="AU" term="%22Alves+APP%22">Alves APP</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Barreto-Reis+E%22">Barreto-Reis E</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Gouvêa+de+Luca+B%22">Gouvêa de Luca B</searchLink>; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Teaching and Research in Histology and Comparative Embryology, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+TS%22">Carvalho TS</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Sciences and Biotechnology Graduate Program, Fluminense Federal University, Niterofi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Andrade+GP%22">de Andrade GP</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Sepúlveda-Fragoso+V%22">Sepúlveda-Fragoso V</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Alexandre-Santos+B%22">Alexandre-Santos B</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Proença+Souza+AB%22">Proença Souza AB</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Souza+Vieira+ALL%22">de Souza Vieira ALL</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Stockler-Pinto+MB%22">Stockler-Pinto MB</searchLink>; Pathology Graduate Program, Fluminense Federal University, Niteroi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Frantz+EDC%22">Frantz EDC</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Exercise Sciences, Fluminense Federal University, Niteroi, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Machado-Santos+C%22">Machado-Santos C</searchLink>; Laboratory of Teaching and Research in Histology and Comparative Embryology, Fluminense Federal University, Niteroi, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Pires+de+Carvalho+D%22">Pires de Carvalho D</searchLink>; Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro (UFRJ), Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Miranda-Alves+L%22">Miranda-Alves L</searchLink>; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; Pharmacology and Medicinal Chemistry Graduate Program, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil; Morphological Sciences Graduate Program, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil.<br /><searchLink fieldCode="AU" term="%22Magliano+DC%22">Magliano DC</searchLink>; Research Center on Morphology and Metabolism, Biomedical Institute, Fluminense Federal University, Niteroi, RJ, Brazil; Laboratory of Experimental Endocrinology, Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Endocrinology Graduate Program, Faculty of Medicine, Federal University of Rio de Janeiro, Brazil; Sciences and Biotechnology Graduate Program, Fluminense Federal University, Niterofi, RJ, Brazil; National Institute of Endocrine Disruptors and Endocrine-Metabolic Repercussions, Brazil. Electronic address: dcmagliano@id.uff.br.
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  Data: <searchLink fieldCode="JN" term="%227500844%22">Molecular and cellular endocrinology</searchLink> [Mol Cell Endocrinol] 2026 Jan 01; Vol. 611, pp. 112689. <i>Date of Electronic Publication: </i>2025 Oct 17.
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