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The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leishmania donovani.

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Title: The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leishmania donovani.
Authors: Aruleba RT; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa., Osero BO; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa., Loots DT; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa., Luies L; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa., Cele Z; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa., Opare PAA; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa., van Reenen M; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa., Brombacher F; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa., Carter KC; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Hurdayal R; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Source: Frontiers in immunology [Front Immunol] 2025 Oct 02; Vol. 16, pp. 1499513. Date of Electronic Publication: 2025 Oct 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leishmania donovani.
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  Data: <searchLink fieldCode="AU" term="%22Aruleba+RT%22">Aruleba RT</searchLink>; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Osero+BO%22">Osero BO</searchLink>; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Loots+DT%22">Loots DT</searchLink>; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa.<br /><searchLink fieldCode="AU" term="%22Luies+L%22">Luies L</searchLink>; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa.<br /><searchLink fieldCode="AU" term="%22Cele+Z%22">Cele Z</searchLink>; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Opare+PAA%22">Opare PAA</searchLink>; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22van+Reenen+M%22">van Reenen M</searchLink>; Focus Area Human Metabolomics, North-West University, Potchefstroom, South Africa.<br /><searchLink fieldCode="AU" term="%22Brombacher+F%22">Brombacher F</searchLink>; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Carter+KC%22">Carter KC</searchLink>; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hurdayal+R%22">Hurdayal R</searchLink>; Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine (IDM), South African Medical Research Council (SAMRC) on Immunology of Infectious Diseases, University of Cape Town, Cape Town, South Africa.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
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