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Anti-inflammatories for depression: challenges and ASPIRations.

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Title: Anti-inflammatories for depression: challenges and ASPIRations.
Authors: Worrell C; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK., Baune BT; Department of Psychiatry, University of Münster, Münster, Germany., Benedetti F; Division of Neuroscience, Psychiatry & Clinical Psychobiology Unit, IRCCS Ospedale San Raffaele, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy., Cattaneo A; Biological Psychiatric Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., De Picker L; University Psychiatric Hospital Campus Duffel, Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute, Faculty of Health Sciences, University of Antwerp, Antwerp, Belgium., Felger JC; Department of Psychiatry and Behavioural Sciences, Emory University School of Medicine, Atlanta, GA, USA., Gold SM; Department of Psychiatry, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin, Germany., Lamers F; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands; Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands., Leboyer M; FondaMental Foundation, Créteil, France; Department of Addictology and Psychiatry, Université Paris-Est Créteil, AP-HP, Translational Neuropsychiatry laboratory, Inserm U955, PEPR PROPSY, Créteil, France., Lombardo G; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK., Mäntylä FL; Global Alliance of Mental Illness Advocacy Networks-Europe, Brussels, Belgium., Miller AH; Department of Psychiatry and Behavioural Sciences, Emory University School of Medicine, Atlanta, GA, USA., Mondelli V; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands; Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands., Sforzini L; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Stein DJ; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Vai B; Division of Neuroscience, Psychiatry & Clinical Psychobiology Unit, IRCCS Ospedale San Raffaele, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy., Van der Eycken E; Global Alliance of Mental Illness Advocacy Networks-Europe, Brussels, Belgium., Woods A; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK., Pariante CM; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK. Electronic address: carmine.pariante@kcl.ac.uk.
Corporate Authors: ASPIRE Study Consortium
Source: The lancet. Psychiatry [Lancet Psychiatry] 2026 Apr; Vol. 13 (4), pp. 277-279. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101638123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2215-0374 (Electronic) Linking ISSN: 22150366 NLM ISO Abbreviation: Lancet Psychiatry Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Worrell+C%22">Worrell C</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Baune+BT%22">Baune BT</searchLink>; Department of Psychiatry, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Benedetti+F%22">Benedetti F</searchLink>; Division of Neuroscience, Psychiatry & Clinical Psychobiology Unit, IRCCS Ospedale San Raffaele, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cattaneo+A%22">Cattaneo A</searchLink>; Biological Psychiatric Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Picker+L%22">De Picker L</searchLink>; University Psychiatric Hospital Campus Duffel, Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute, Faculty of Health Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Felger+JC%22">Felger JC</searchLink>; Department of Psychiatry and Behavioural Sciences, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Gold+SM%22">Gold SM</searchLink>; Department of Psychiatry, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lamers+F%22">Lamers F</searchLink>; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands; Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Leboyer+M%22">Leboyer M</searchLink>; FondaMental Foundation, Créteil, France; Department of Addictology and Psychiatry, Université Paris-Est Créteil, AP-HP, Translational Neuropsychiatry laboratory, Inserm U955, PEPR PROPSY, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Lombardo+G%22">Lombardo G</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Mäntylä+FL%22">Mäntylä FL</searchLink>; Global Alliance of Mental Illness Advocacy Networks-Europe, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Miller+AH%22">Miller AH</searchLink>; Department of Psychiatry and Behavioural Sciences, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Mondelli+V%22">Mondelli V</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Penninx+BWJH%22">Penninx BWJH</searchLink>; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands; Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sforzini+L%22">Sforzini L</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Stein+DJ%22">Stein DJ</searchLink>; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Vai+B%22">Vai B</searchLink>; Division of Neuroscience, Psychiatry & Clinical Psychobiology Unit, IRCCS Ospedale San Raffaele, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Van+der+Eycken+E%22">Van der Eycken E</searchLink>; Global Alliance of Mental Illness Advocacy Networks-Europe, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Woods+A%22">Woods A</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK.<br /><searchLink fieldCode="AU" term="%22Pariante+CM%22">Pariante CM</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 9RT, UK; National Institute for Health and Care Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK. Electronic address: carmine.pariante@kcl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101638123%22">The lancet. Psychiatry</searchLink> [Lancet Psychiatry] 2026 Apr; Vol. 13 (4), pp. 277-279. <i>Date of Electronic Publication: </i>2025 Oct 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101638123 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2215-0374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222150366%22">22150366 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Psychiatry <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 Apr
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