The evolving landscape of leptomeningeal metastases from NSCLC: an international, contemporary, multicenter cohort study.

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Title: The evolving landscape of leptomeningeal metastases from NSCLC: an international, contemporary, multicenter cohort study.
Authors: Zheng MM; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China., Xia Y; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China., Pan K; Department of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, USA., Sun F; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA., Tan AC; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Dong XR; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Tu HY; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China., Tang LB; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China., Li YS; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China., Yin K; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China., Borgeaud M; Department of Oncology, University Hospital Geneva, Geneva, Switzerland., Singhal S; Division of Hematology/Oncology, UC Davis Comprehensive Cancer Center, Sacramento, USA., Zhu E; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Zhang J; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Nilsson M; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Wu J; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, USA., Gibbons DL; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Wakelee H; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA., Neal JW; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA., Lee J; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, USA., Vaporciyan AA; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, USA., Ringsurongkawong W; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Tran HT; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Zhang RZ; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P. R. China., Zhang T; Department of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China., Zhou Q; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China., Zhong WZ; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China., Li W; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China., Zhang YC; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P. R. China., Riess JW; Division of Hematology/Oncology, UC Davis Comprehensive Cancer Center, Sacramento, USA., Addeo A; Department of Oncology, University Hospital Geneva, Geneva, Switzerland., Heymach JV; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA., Myall N; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA., Tan D; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Wu YL; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China. Electronic address: syylwu@live.cn., Le X; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address: xle1@mdanderson.org.
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2026 Jan; Vol. 37 (1), pp. 104-116. Date of Electronic Publication: 2025 Oct 20.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zheng+MM%22">Zheng MM</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Xia+Y%22">Xia Y</searchLink>; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Pan+K%22">Pan K</searchLink>; Department of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Sun+F%22">Sun F</searchLink>; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Tan+AC%22">Tan AC</searchLink>; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Dong+XR%22">Dong XR</searchLink>; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Tu+HY%22">Tu HY</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Tang+LB%22">Tang LB</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+YS%22">Li YS</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Yin+K%22">Yin K</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Borgeaud+M%22">Borgeaud M</searchLink>; Department of Oncology, University Hospital Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Singhal+S%22">Singhal S</searchLink>; Division of Hematology/Oncology, UC Davis Comprehensive Cancer Center, Sacramento, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+E%22">Zhu E</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Nilsson+M%22">Nilsson M</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Gibbons+DL%22">Gibbons DL</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Wakelee+H%22">Wakelee H</searchLink>; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Neal+JW%22">Neal JW</searchLink>; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Vaporciyan+AA%22">Vaporciyan AA</searchLink>; Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Ringsurongkawong+W%22">Ringsurongkawong W</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Tran+HT%22">Tran HT</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+RZ%22">Zhang RZ</searchLink>; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+T%22">Zhang T</searchLink>; Department of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhong+WZ%22">Zhong WZ</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+YC%22">Zhang YC</searchLink>; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P. R. China.<br /><searchLink fieldCode="AU" term="%22Riess+JW%22">Riess JW</searchLink>; Division of Hematology/Oncology, UC Davis Comprehensive Cancer Center, Sacramento, USA.<br /><searchLink fieldCode="AU" term="%22Addeo+A%22">Addeo A</searchLink>; Department of Oncology, University Hospital Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Heymach+JV%22">Heymach JV</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Myall+N%22">Myall N</searchLink>; Division of Oncology, Department of Medicine, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Tan+D%22">Tan D</searchLink>; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wu+YL%22">Wu YL</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, P. R. China; Guangdong Provincial Key Laboratory of Translation Medicine in Lung Cancer, Guangzhou, P. R. China. Electronic address: syylwu@live.cn.<br /><searchLink fieldCode="AU" term="%22Le+X%22">Le X</searchLink>; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address: xle1@mdanderson.org.
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  Data: <searchLink fieldCode="JN" term="%229007735%22">Annals of oncology : official journal of the European Society for Medical Oncology</searchLink> [Ann Oncol] 2026 Jan; Vol. 37 (1), pp. 104-116. <i>Date of Electronic Publication: </i>2025 Oct 20.
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