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Predictors of Successful Secukinumab Dose Tapering in Moderate-to-Severe Psoriasis: A Retrospective Study.

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Title: Predictors of Successful Secukinumab Dose Tapering in Moderate-to-Severe Psoriasis: A Retrospective Study.
Authors: Chen J; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Xiao Z; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Zeng X; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Xiang N; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Luo R; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Chen R; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Lin B; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Ke H; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China., Gong T; Department of Dermatology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Ji C; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.
Source: Psoriasis (Auckland, N.Z.) [Psoriasis (Auckl)] 2025 Oct 17; Vol. 15, pp. 527-534. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101709086 Publication Model: eCollection Cited Medium: Internet ISSN: 2230-326X (Electronic) Linking ISSN: 2230326X NLM ISO Abbreviation: Psoriasis (Auckl) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Predictors of Successful Secukinumab Dose Tapering in Moderate-to-Severe Psoriasis: A Retrospective Study.
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  Data: <searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xiao+Z%22">Xiao Z</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xiang+N%22">Xiang N</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Luo+R%22">Luo R</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ke+H%22">Ke H</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gong+T%22">Gong T</searchLink>; Department of Dermatology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ji+C%22">Ji C</searchLink>; Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Fujian Provincial Clinical Research Center for Immune Skin Diseases, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Institute of Dermatology, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.; Key Laboratory of skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, People's Republic of China.
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        Value: 10.2147/PTT.S531447
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              Text: 2025 Oct 17
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