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Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.

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Title: Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.
Authors: Wearn A; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada., Tardif CL; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.; McConnell Brain Imaging Centre, McGill University, Montreal, QC H3A 2B4, Canada., Leppert IR; McConnell Brain Imaging Centre, McGill University, Montreal, QC H3A 2B4, Canada., Baracchini G; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada., Hughes C; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada., Tremblay-Mercier J; Douglas Mental Health University Institute, Verdun, QC H4H 1R3, Canada., Breitner J; Douglas Mental Health University Institute, Verdun, QC H4H 1R3, Canada.; Departments of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada., Poirier J; Douglas Mental Health University Institute, Verdun, QC H4H 1R3, Canada., Villeneuve S; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.; McConnell Brain Imaging Centre, McGill University, Montreal, QC H3A 2B4, Canada.; Douglas Mental Health University Institute, Verdun, QC H4H 1R3, Canada., Bernhardt BC; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada., Turner GR; Department of Psychology, York University, Toronto, ON M3J 1P3, Canada., Spreng RN; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.; McConnell Brain Imaging Centre, McGill University, Montreal, QC H3A 2B4, Canada.; Douglas Mental Health University Institute, Verdun, QC H4H 1R3, Canada.; Departments of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada.; Department of Psychology, McGill University, Montreal, QC H3A 3E8, Canada.
Corporate Authors: PREVENT-AD Research Group
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 04; Vol. 122 (44), pp. e2502674122. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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