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[18F]FDG-PET/CT's change in total lesion glycolysis can accurately identify early response upon neoadjuvant immunotherapy prior to curative-intent surgery in cutaneous squamous cell carcinoma; MATISSE trial.

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Title: [18F]FDG-PET/CT's change in total lesion glycolysis can accurately identify early response upon neoadjuvant immunotherapy prior to curative-intent surgery in cutaneous squamous cell carcinoma; MATISSE trial.
Authors: Breukers SE; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. s.breukers@nki.nl.; Antoni Van Leeuwenhoek (NKI-AVL), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. s.breukers@nki.nl., Crommelin RD; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Smit LA; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., de Boer JP; Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Navran A; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., van Houdt WJ; Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., de Bree R; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Devriese LA; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Haanen JBAG; Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Wondergem M; Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Zuur CL; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otorhinolaryngology Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands., Vogel WV; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. w.vogel@nki.nl.; Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands. w.vogel@nki.nl.; Antoni Van Leeuwenhoek (NKI-AVL), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. w.vogel@nki.nl.
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Mar; Vol. 53 (4), pp. 2217-2233. Date of Electronic Publication: 2025 Oct 28.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
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  Data: [<superscript>18</superscript>F]FDG-PET/CT's change in total lesion glycolysis can accurately identify early response upon neoadjuvant immunotherapy prior to curative-intent surgery in cutaneous squamous cell carcinoma; MATISSE trial.
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  Data: <searchLink fieldCode="AU" term="%22Breukers+SE%22">Breukers SE</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. s.breukers@nki.nl.; Antoni Van Leeuwenhoek (NKI-AVL), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. s.breukers@nki.nl.<br /><searchLink fieldCode="AU" term="%22Crommelin+RD%22">Crommelin RD</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+LA%22">Smit LA</searchLink>; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Boer+JP%22">de Boer JP</searchLink>; Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Navran+A%22">Navran A</searchLink>; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Houdt+WJ%22">van Houdt WJ</searchLink>; Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Bree+R%22">de Bree R</searchLink>; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Devriese+LA%22">Devriese LA</searchLink>; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Haanen+JBAG%22">Haanen JBAG</searchLink>; Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wondergem+M%22">Wondergem M</searchLink>; Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zuur+CL%22">Zuur CL</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otorhinolaryngology Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vogel+WV%22">Vogel WV</searchLink>; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. w.vogel@nki.nl.; Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands. w.vogel@nki.nl.; Antoni Van Leeuwenhoek (NKI-AVL), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. w.vogel@nki.nl.
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  Data: <searchLink fieldCode="JN" term="%22101140988%22">European journal of nuclear medicine and molecular imaging</searchLink> [Eur J Nucl Med Mol Imaging] 2026 Mar; Vol. 53 (4), pp. 2217-2233. <i>Date of Electronic Publication: </i>2025 Oct 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Berlin%22">Springer-Verlag Berlin </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101140988 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1619-7089 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216197070%22">16197070 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Nucl Med Mol Imaging <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar
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