KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression.

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Title: KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression.
Authors: Rampias T; Biomedical Research Foundation Academy of Athens, Athens, Greece. trampias@bioacademy.gr., Goutas A; Biomedical Research Foundation Academy of Athens, Athens, Greece., Karagiannis D; Biomedical Research Foundation Academy of Athens, Athens, Greece., Kanaki Z; Biomedical Research Foundation Academy of Athens, Athens, Greece., Makri A; Biomedical Research Foundation Academy of Athens, Athens, Greece., Hoxhallari L; Biomedical Research Foundation Academy of Athens, Athens, Greece., Koukouzeli FE; Biomedical Research Foundation Academy of Athens, Athens, Greece., Paraskevopoulou V; Biomedical Research Foundation Academy of Athens, Athens, Greece., Tsouraki D; Biomedical Research Foundation Academy of Athens, Athens, Greece., Paschalidis N; Biomedical Research Foundation Academy of Athens, Athens, Greece., Avgeris M; Laboratory of Clinical Biochemistry-Molecular Diagnostics, Second Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece., Scorilas A; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece., Klinakis A; Biomedical Research Foundation Academy of Athens, Athens, Greece. aklinakis@bioacademy.gr.
Source: NPJ precision oncology [NPJ Precis Oncol] 2025 Oct 28; Vol. 9 (1), pp. 336. Date of Electronic Publication: 2025 Oct 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
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  Data: KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression.
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  Data: <searchLink fieldCode="AU" term="%22Rampias+T%22">Rampias T</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece. trampias@bioacademy.gr.<br /><searchLink fieldCode="AU" term="%22Goutas+A%22">Goutas A</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Karagiannis+D%22">Karagiannis D</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kanaki+Z%22">Kanaki Z</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Makri+A%22">Makri A</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Hoxhallari+L%22">Hoxhallari L</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Koukouzeli+FE%22">Koukouzeli FE</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Paraskevopoulou+V%22">Paraskevopoulou V</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tsouraki+D%22">Tsouraki D</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Paschalidis+N%22">Paschalidis N</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Avgeris+M%22">Avgeris M</searchLink>; Laboratory of Clinical Biochemistry-Molecular Diagnostics, Second Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Scorilas+A%22">Scorilas A</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Klinakis+A%22">Klinakis A</searchLink>; Biomedical Research Foundation Academy of Athens, Athens, Greece. aklinakis@bioacademy.gr.
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  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2025 Oct 28; Vol. 9 (1), pp. 336. <i>Date of Electronic Publication: </i>2025 Oct 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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