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Retrospective multicenter cohort study of slow titration of vortioxetine to mitigate early nausea in major depression.

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Title: Retrospective multicenter cohort study of slow titration of vortioxetine to mitigate early nausea in major depression.
Authors: Fagiolini A; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: andreafagiolini@gmail.com., Aguglia A; IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Psychiatry, University of Genoa, Italy. Electronic address: andrea.aguglia@unige.it., Bondi E; ASST Papa Giovanni XXIII, Bergamo, Italy. Electronic address: ebondi@asst-pg23.it., Bussolotti D; Department of Mental Health and Addictions, ASST Mantua, 46100 Mantua, Italy. Electronic address: debora.bussolotti@asst-mantova.it., Caldiroli A; Fondazione IRCCS San Gerardo dei Tintori, via G.B. Pergolesi 33, 20900, Monza, MB, Italy. Electronic address: alice.caldiroli@irccs-sangerardo.it., Carmellini P; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: carnellinip@gmail.com., Clerici M; University of Milano Bicocca, Italy. Electronic address: massimo.clerici@unimib.it., De Berardis D; Department of Mental Health, ASL 4 Teramo, Italy. Electronic address: domenico.deberardis@aslteramo.it., De Filippis S; Villa Von Siebenthal Clinic, Rome, Italy. Electronic address: sergio.defilippis@me.com., Koukouna D; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: koukounadespoina@gmail.com., Libri C; ASST Papa Giovanni XXIII, Bergamo, Italy. Electronic address: clibri@asst-pg23.it., Menculini G; Section of Psychiatry, Department of Medicine and Surgery, University of Perugia, Italy. Electronic address: giulia.menculini@unipg.it., Pardossi S; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: s.pardossi@student.unisi.it., Pinzi M; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: mario.pinzi@student.unisi.it., Rescalli B; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: m.rescalli@student.unisi.it., Tortorella A; Section of Psychiatry, Department of Medicine and Surgery, University of Perugia, Italy. Electronic address: alfonso.tortorella@unipg.it., Trovini G; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy; Villa Von Siebenthal Clinic, Rome, Italy. Electronic address: g.trovini@student.unisi.it., Cuomo A; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: alessandrocuomo86@gmail.com.
Source: Journal of affective disorders [J Affect Disord] 2026 Feb 01; Vol. 394 (Pt A), pp. 120562. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Retrospective multicenter cohort study of slow titration of vortioxetine to mitigate early nausea in major depression.
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  Data: <searchLink fieldCode="AU" term="%22Fagiolini+A%22">Fagiolini A</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: andreafagiolini@gmail.com.<br /><searchLink fieldCode="AU" term="%22Aguglia+A%22">Aguglia A</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Psychiatry, University of Genoa, Italy. Electronic address: andrea.aguglia@unige.it.<br /><searchLink fieldCode="AU" term="%22Bondi+E%22">Bondi E</searchLink>; ASST Papa Giovanni XXIII, Bergamo, Italy. Electronic address: ebondi@asst-pg23.it.<br /><searchLink fieldCode="AU" term="%22Bussolotti+D%22">Bussolotti D</searchLink>; Department of Mental Health and Addictions, ASST Mantua, 46100 Mantua, Italy. Electronic address: debora.bussolotti@asst-mantova.it.<br /><searchLink fieldCode="AU" term="%22Caldiroli+A%22">Caldiroli A</searchLink>; Fondazione IRCCS San Gerardo dei Tintori, via G.B. Pergolesi 33, 20900, Monza, MB, Italy. Electronic address: alice.caldiroli@irccs-sangerardo.it.<br /><searchLink fieldCode="AU" term="%22Carmellini+P%22">Carmellini P</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: carnellinip@gmail.com.<br /><searchLink fieldCode="AU" term="%22Clerici+M%22">Clerici M</searchLink>; University of Milano Bicocca, Italy. Electronic address: massimo.clerici@unimib.it.<br /><searchLink fieldCode="AU" term="%22De+Berardis+D%22">De Berardis D</searchLink>; Department of Mental Health, ASL 4 Teramo, Italy. Electronic address: domenico.deberardis@aslteramo.it.<br /><searchLink fieldCode="AU" term="%22De+Filippis+S%22">De Filippis S</searchLink>; Villa Von Siebenthal Clinic, Rome, Italy. Electronic address: sergio.defilippis@me.com.<br /><searchLink fieldCode="AU" term="%22Koukouna+D%22">Koukouna D</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: koukounadespoina@gmail.com.<br /><searchLink fieldCode="AU" term="%22Libri+C%22">Libri C</searchLink>; ASST Papa Giovanni XXIII, Bergamo, Italy. Electronic address: clibri@asst-pg23.it.<br /><searchLink fieldCode="AU" term="%22Menculini+G%22">Menculini G</searchLink>; Section of Psychiatry, Department of Medicine and Surgery, University of Perugia, Italy. Electronic address: giulia.menculini@unipg.it.<br /><searchLink fieldCode="AU" term="%22Pardossi+S%22">Pardossi S</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: s.pardossi@student.unisi.it.<br /><searchLink fieldCode="AU" term="%22Pinzi+M%22">Pinzi M</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: mario.pinzi@student.unisi.it.<br /><searchLink fieldCode="AU" term="%22Rescalli+B%22">Rescalli B</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: m.rescalli@student.unisi.it.<br /><searchLink fieldCode="AU" term="%22Tortorella+A%22">Tortorella A</searchLink>; Section of Psychiatry, Department of Medicine and Surgery, University of Perugia, Italy. Electronic address: alfonso.tortorella@unipg.it.<br /><searchLink fieldCode="AU" term="%22Trovini+G%22">Trovini G</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy; Villa Von Siebenthal Clinic, Rome, Italy. Electronic address: g.trovini@student.unisi.it.<br /><searchLink fieldCode="AU" term="%22Cuomo+A%22">Cuomo A</searchLink>; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Siena, Italy. Electronic address: alessandrocuomo86@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%227906073%22">Journal of affective disorders</searchLink> [J Affect Disord] 2026 Feb 01; Vol. 394 (Pt A), pp. 120562. <i>Date of Electronic Publication: </i>2025 Oct 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2FNorth-Holland+Biomedical+Press%22">Elsevier/North-Holland Biomedical Press </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7906073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2517 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201650327%22">01650327 </searchLink><i>NLM ISO Abbreviation: </i>J Affect Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jad.2025.120562
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        Text: English
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              Text: 2026 Feb 01
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