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Preclinical in vitro and in vivo evaluation of omadacycline against multidrug-resistant Acinetobacter baumannii.

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Title: Preclinical in vitro and in vivo evaluation of omadacycline against multidrug-resistant Acinetobacter baumannii.
Authors: Vanachayangkul P; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Ruamsap N; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Caridha D; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Imerbsin R; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Ball E; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Chattagul S; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Tungtang A; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Gonwong S; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Kodchakorn C; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Lertsethtakarn P; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Silapong S; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Chaisatit C; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Khemnu N; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Boudreaux D; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Boonyalai N; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Demons S; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Pierce JV; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA., Martin M; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Anastasiou D; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA., Serio AW; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA., Vesely B; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand., Lanteri CA; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Dec 10; Vol. 69 (12), pp. e0093225. Date of Electronic Publication: 2025 Oct 30.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preclinical in vitro and in vivo evaluation of omadacycline against multidrug-resistant Acinetobacter baumannii.
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  Data: <searchLink fieldCode="AU" term="%22Vanachayangkul+P%22">Vanachayangkul P</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Ruamsap+N%22">Ruamsap N</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Caridha+D%22">Caridha D</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Imerbsin+R%22">Imerbsin R</searchLink>; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Ball+E%22">Ball E</searchLink>; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Chattagul+S%22">Chattagul S</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Tungtang+A%22">Tungtang A</searchLink>; Department of Veterinary Medicine, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Gonwong+S%22">Gonwong S</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Kodchakorn+C%22">Kodchakorn C</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Lertsethtakarn+P%22">Lertsethtakarn P</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Silapong+S%22">Silapong S</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Chaisatit+C%22">Chaisatit C</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Khemnu+N%22">Khemnu N</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Boudreaux+D%22">Boudreaux D</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Boonyalai+N%22">Boonyalai N</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Demons+S%22">Demons S</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Pierce+JV%22">Pierce JV</searchLink>; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Martin+M%22">Martin M</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Anastasiou+D%22">Anastasiou D</searchLink>; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Serio+AW%22">Serio AW</searchLink>; Paratek Pharmaceuticals Inc., King of Prussia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Vesely+B%22">Vesely B</searchLink>; Department of Bacterial and Parasitic Diseases, Walter Reed Army Institute of Research-Armed Forces Research Institute of Medical Science, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Lanteri+CA%22">Lanteri CA</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
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