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TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1.

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Title: TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1.
Authors: Lu Y; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China.; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China., Chen Y; Department of Cardiology, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210008, China., Pan X; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medical, Nanjing, Jiangsu, 210008, China., Ma W; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China., Liu N; Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210001, China., Yang L; Clinical and Translational Research Center, Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu, 226001, China., Dong X; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China., Guo H; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China., Li D; State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-Embryology, Medical School, Nanjing University, No. 22 Hankou Road, Nanjing, Jiangsu Province, 210093, People's Republic of China. lidm@nju.edu.cn.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu, 210093, China. lidm@nju.edu.cn., Gan W; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China. gwd@nju.edu.cn.; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medical, Nanjing, Jiangsu, 210008, China. gwd@nju.edu.cn.; No. 321 Zhongshan Road, Nanjing, Jiangsu Province, 210008, People's Republic of China. gwd@nju.edu.cn.
Source: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2025 Dec; Vol. 48 (6), pp. 2035-2053. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1.
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  Data: <searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China.; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Cardiology, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210008, China.<br /><searchLink fieldCode="AU" term="%22Pan+X%22">Pan X</searchLink>; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medical, Nanjing, Jiangsu, 210008, China.<br /><searchLink fieldCode="AU" term="%22Ma+W%22">Ma W</searchLink>; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210001, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Clinical and Translational Research Center, Department of Oncology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu, 226001, China.<br /><searchLink fieldCode="AU" term="%22Dong+X%22">Dong X</searchLink>; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-Embryology, Medical School, Nanjing University, No. 22 Hankou Road, Nanjing, Jiangsu Province, 210093, People's Republic of China. lidm@nju.edu.cn.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu, 210093, China. lidm@nju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gan+W%22">Gan W</searchLink>; Department of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, 210093, China. gwd@nju.edu.cn.; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medical, Nanjing, Jiangsu, 210008, China. gwd@nju.edu.cn.; No. 321 Zhongshan Road, Nanjing, Jiangsu Province, 210008, People's Republic of China. gwd@nju.edu.cn.
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              Text: 2025 Dec
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              Y: 2025
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